Diagnosis and management of pain in Parkinson’s disease: a new approach

Abstract: Pain is a frequent and disabling non-motor feature of Parkinson’s disease (PD). The recently proposed PD Pain Classification System (PD-PCS) allows to determine an association of pain with PD before allocating to the main pain mechanism (i.e. nociceptive, neuropathic, and nociplastic). In...

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Autores principales: Mylius, Veit, Carsten Möller, Jens, Bohlhalter, Stephan, Ciampi de Andrade, Daniel, Pérez Lloret, Santiago
Formato: Artículo
Lenguaje:Inglés
Publicado: Springer 2021
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Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/12862
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spelling I33-R139-123456789-128622023-11-22T22:05:05Z Diagnosis and management of pain in Parkinson’s disease: a new approach Mylius, Veit Carsten Möller, Jens Bohlhalter, Stephan Ciampi de Andrade, Daniel Pérez Lloret, Santiago ENFERMEDAD DE PARKINSON DIAGNOSTICO DOLOR TRATAMIENTO MEDICO Abstract: Pain is a frequent and disabling non-motor feature of Parkinson’s disease (PD). The recently proposed PD Pain Classification System (PD-PCS) allows to determine an association of pain with PD before allocating to the main pain mechanism (i.e. nociceptive, neuropathic, and nociplastic). In this article, previous studies on treatments for pain in PD are summarized according to the pain mechanisms. A mechanistic approach to treatment is discussed. We suggest that the first step should be optimizing dopaminergic therapy before other therapy is started. When these treatments remain unsuccessful, further causes of pain must be considered. The role of drugs, invasive treatments, and physiotherapeutic interventions are discussed with a focus on older PD patients considering polypharmacy, altered pharmacokinetics, and comorbidities. 2021-11-11T22:43:11Z 2021-11-11T22:43:11Z 2021 Artículo Mylius, V., et al. Diagnosis and management of pain in Parkinson’s disease: a new approach [en línea]. Drugs & Aging. 2021, 38. doi:10.1007/s40266-021-00867-1. Disponible en: https://repositorio.uca.edu.ar/handle/123456789/12862 170-229X (impreso) 1179-1969 (online) https://repositorio.uca.edu.ar/handle/123456789/12862 10.1007/s40266-021-00867-1 34224103 eng Acceso abierto. 12 meses de embargo http://creativecommons.org/licenses/by-nc-sa/4.0/ application/pdf Springer Drugs & Aging. 2021, 38. doi:10.1007/s40266-021-00867-1
institution Universidad Católica Argentina
institution_str I-33
repository_str R-139
collection Repositorio Institucional de la Universidad Católica Argentina (UCA)
language Inglés
topic ENFERMEDAD DE PARKINSON
DIAGNOSTICO
DOLOR
TRATAMIENTO MEDICO
spellingShingle ENFERMEDAD DE PARKINSON
DIAGNOSTICO
DOLOR
TRATAMIENTO MEDICO
Mylius, Veit
Carsten Möller, Jens
Bohlhalter, Stephan
Ciampi de Andrade, Daniel
Pérez Lloret, Santiago
Diagnosis and management of pain in Parkinson’s disease: a new approach
topic_facet ENFERMEDAD DE PARKINSON
DIAGNOSTICO
DOLOR
TRATAMIENTO MEDICO
description Abstract: Pain is a frequent and disabling non-motor feature of Parkinson’s disease (PD). The recently proposed PD Pain Classification System (PD-PCS) allows to determine an association of pain with PD before allocating to the main pain mechanism (i.e. nociceptive, neuropathic, and nociplastic). In this article, previous studies on treatments for pain in PD are summarized according to the pain mechanisms. A mechanistic approach to treatment is discussed. We suggest that the first step should be optimizing dopaminergic therapy before other therapy is started. When these treatments remain unsuccessful, further causes of pain must be considered. The role of drugs, invasive treatments, and physiotherapeutic interventions are discussed with a focus on older PD patients considering polypharmacy, altered pharmacokinetics, and comorbidities.
format Artículo
author Mylius, Veit
Carsten Möller, Jens
Bohlhalter, Stephan
Ciampi de Andrade, Daniel
Pérez Lloret, Santiago
author_facet Mylius, Veit
Carsten Möller, Jens
Bohlhalter, Stephan
Ciampi de Andrade, Daniel
Pérez Lloret, Santiago
author_sort Mylius, Veit
title Diagnosis and management of pain in Parkinson’s disease: a new approach
title_short Diagnosis and management of pain in Parkinson’s disease: a new approach
title_full Diagnosis and management of pain in Parkinson’s disease: a new approach
title_fullStr Diagnosis and management of pain in Parkinson’s disease: a new approach
title_full_unstemmed Diagnosis and management of pain in Parkinson’s disease: a new approach
title_sort diagnosis and management of pain in parkinson’s disease: a new approach
publisher Springer
publishDate 2021
url https://repositorio.uca.edu.ar/handle/123456789/12862
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AT bohlhalterstephan diagnosisandmanagementofpaininparkinsonsdiseaseanewapproach
AT ciampideandradedaniel diagnosisandmanagementofpaininparkinsonsdiseaseanewapproach
AT perezlloretsantiago diagnosisandmanagementofpaininparkinsonsdiseaseanewapproach
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