Detection of COVID-19 patients in sweat samples using canine sense of smell: Preliminary study

Volatile Organic Compounds generated by changes in the metabolism of an individual have been used for the diagnosis of diseases through canine sense of smell. There is evidence of the generation of these compounds in SARS-COV-2 infection. The objective of the work was to determine the canine capacit...

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Autores principales: Álvarez, G., Carancci, P., De los Santos, F., Zapata, A., Lorenzo, H. R.
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional del Nordeste 2023
Materias:
COVID-19
componentes orgánicos volátiles
olfato canino
volatile organic components
canine sense of smell
Acceso en línea:https://revistas.unne.edu.ar/index.php/vet/article/view/6604
Aporte de:
Revistas UNNE - Universidad Nacional del Noroeste (UNNE) de Universidad Nacional del Nordeste
id I48-R154-article-6604
record_format ojs
spelling I48-R154-article-66042023-06-05T13:03:26Z Detection of COVID-19 patients in sweat samples using canine sense of smell: Preliminary study Detección de pacientes COVID-19 en muestras de sudor por medio del olfato canino: Estudio preliminar Álvarez, G. Carancci, P. De los Santos, F. Zapata, A. Lorenzo, H. R. COVID-19 componentes orgánicos volátiles olfato canino COVID-19 volatile organic components canine sense of smell Volatile Organic Compounds generated by changes in the metabolism of an individual have been used for the diagnosis of diseases through canine sense of smell. There is evidence of the generation of these compounds in SARS-COV-2 infection. The objective of the work was to determine the canine capacity to discriminate between positive and negative patients with COVID-19 through samples of axillary sweat. Axillary sweat samples were used from 102 hospitalized patients both COVID-19 positive (31) and negative (71), all diagnosed by rt-PCR test. For each round of detection, a single positive sample was placed and the rest of the samples (whether 1, 2, 3, 4, or 5) were negative. The overall sensitivity and specificity were 93.11% (± 3.14%) and 88.52% (± 4.64%) respectively. The high sensitivity could be due to the longer train­ing thus increasing the accuracy in the detection of positive samples. The specificity was than lower another published and may be due to the fact that the negative samples came from people hospitalized for other pathologies or were companions of hospitalized family members, so that all had a hospitable odor. Detecting COVID-19 patients using canine smell has proven to be a reliable and promising sieve test. Los componentes orgánicos volátiles generados por cambios en el metabolismo de un individuo han sido utilizados para el diagnóstico de enfermedades a través del olfato canino. Hay evidencias sobre la generación de dichos componentes en la infección por SARS-COV-2. El objetivo del trabajo fue determinar la capacidad canina para discriminar a pacientes positivos y negativos a COVID-19 a través de muestras de sudor axilar. Se utilizaron muestras de sudor axilar de 102 pacientes hospitalizados tanto COVID-19 positivos (31) como negativos (71), todos diagnosticados mediante la prueba de RT-PCR. Por cada ronda de detección se colocó una única muestra positiva y el resto de las muestras (sean 1, 2, 3, 4 o 5) negativas. La sensibilidad y especificidad global fue de 93,11% (± 3,14%) y 88,52% (± 4,64%) respectivamente. La alta sensibilidad pudo deberse al entrenamiento más prolongado aumentando así, la exactitud en la detección de muestras positivas. La especificidad fue menor a otra publicada pudiéndose deber a que las muestras negativas provenían de personas internadas por otras patologías o eran acompañantes de familiares internados por lo que todas poseían olor hospitalario. La detección de pacientes COVID-19 mediante el olfato canino ha demostrado ser una prueba tamiz confiable y prometedora. Universidad Nacional del Nordeste 2023-06-05 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unne.edu.ar/index.php/vet/article/view/6604 10.30972/vet.3416604 Revista Veterinaria; Vol. 34 Núm. 1 (2023); 6-13 1669-6840 1668-4834 spa https://revistas.unne.edu.ar/index.php/vet/article/view/6604/6143 Derechos de autor 2023 Revista Veterinaria
institution Universidad Nacional del Nordeste
institution_str I-48
repository_str R-154
container_title_str Revistas UNNE - Universidad Nacional del Noroeste (UNNE)
language Español
format Artículo revista
topic COVID-19
componentes orgánicos volátiles
olfato canino
COVID-19
volatile organic components
canine sense of smell
spellingShingle COVID-19
componentes orgánicos volátiles
olfato canino
COVID-19
volatile organic components
canine sense of smell
Álvarez, G.
Carancci, P.
De los Santos, F.
Zapata, A.
Lorenzo, H. R.
Detection of COVID-19 patients in sweat samples using canine sense of smell: Preliminary study
topic_facet COVID-19
componentes orgánicos volátiles
olfato canino
COVID-19
volatile organic components
canine sense of smell
author Álvarez, G.
Carancci, P.
De los Santos, F.
Zapata, A.
Lorenzo, H. R.
author_facet Álvarez, G.
Carancci, P.
De los Santos, F.
Zapata, A.
Lorenzo, H. R.
author_sort Álvarez, G.
title Detection of COVID-19 patients in sweat samples using canine sense of smell: Preliminary study
title_short Detection of COVID-19 patients in sweat samples using canine sense of smell: Preliminary study
title_full Detection of COVID-19 patients in sweat samples using canine sense of smell: Preliminary study
title_fullStr Detection of COVID-19 patients in sweat samples using canine sense of smell: Preliminary study
title_full_unstemmed Detection of COVID-19 patients in sweat samples using canine sense of smell: Preliminary study
title_sort detection of covid-19 patients in sweat samples using canine sense of smell: preliminary study
description Volatile Organic Compounds generated by changes in the metabolism of an individual have been used for the diagnosis of diseases through canine sense of smell. There is evidence of the generation of these compounds in SARS-COV-2 infection. The objective of the work was to determine the canine capacity to discriminate between positive and negative patients with COVID-19 through samples of axillary sweat. Axillary sweat samples were used from 102 hospitalized patients both COVID-19 positive (31) and negative (71), all diagnosed by rt-PCR test. For each round of detection, a single positive sample was placed and the rest of the samples (whether 1, 2, 3, 4, or 5) were negative. The overall sensitivity and specificity were 93.11% (± 3.14%) and 88.52% (± 4.64%) respectively. The high sensitivity could be due to the longer train­ing thus increasing the accuracy in the detection of positive samples. The specificity was than lower another published and may be due to the fact that the negative samples came from people hospitalized for other pathologies or were companions of hospitalized family members, so that all had a hospitable odor. Detecting COVID-19 patients using canine smell has proven to be a reliable and promising sieve test.
publisher Universidad Nacional del Nordeste
publishDate 2023
url https://revistas.unne.edu.ar/index.php/vet/article/view/6604
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first_indexed 2024-08-21T22:35:48Z
last_indexed 2024-08-21T22:35:48Z
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