Hypoglycemia as paraneoplastic syndrome in a Fox terrier canine with leiomyoma in the gastric wall
The aim of this study was to evaluate the clinical progression of hypoglycemia as a paraneoplastic syndrome in a dog diagnosed with gastric wall leiomyoma. A 10-yeaxr-old female Fox Terrier was presented with abdominal distension, lethargy, and weakness. Hematological evaluation showed normal comple...
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| Formato: | Artículo revista |
| Lenguaje: | Español |
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Universidad Nacional del Nordeste
2025
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| Acceso en línea: | https://revistas.unne.edu.ar/index.php/vet/article/view/8606 |
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I48-R154-article-86062025-09-02T21:00:48Z Hypoglycemia as paraneoplastic syndrome in a Fox terrier canine with leiomyoma in the gastric wall Hipoglucemia como síndrome paraneoplásico en un canino de raza Fox terrier con leiomioma gástrico Britez-Valinotti, C. E. Olivo, M. Unzain Meneses, J. A. Cardozo Areco, W. V. González-Vatteone, R. Canine leiomyoma hypoglycemia Canino leiomioma hipoglucemia The aim of this study was to evaluate the clinical progression of hypoglycemia as a paraneoplastic syndrome in a dog diagnosed with gastric wall leiomyoma. A 10-yeaxr-old female Fox Terrier was presented with abdominal distension, lethargy, and weakness. Hematological evaluation showed normal complete blood count and renal profile, while the liver profile revealed elevated alkaline phosphatase and GPT. Electrolytes (Ca, P, K, Na) were within normal limits, but blood glucose was markedly decreased (35 mg dl-1). Abdominal ultrasonography revealed a mixed-echogenic mass in the epigastric region with positive Doppler signal. The patient was stabilized with 1 ml kg-1 of 50% dextrose and maintained on 5% isotonic glucose solution; however, hypoglycemia recurred upon suspension of glucose therapy. An exploratory laparotomy was performed, revealing a pedunculated, circular mass (14 x 9 x 8 cm) attached to the greater curvature of the stomach, without adhesions, and multiple hepatic nodules. The mass was excised, and the liver biopsies were obtained. Remarkably, blood glucose levels stabilized immediately after tumor removal. Histopathology confirmed the diagnosis of gastric leiomyoma. The dog remained asymptomatic, with normal glycemia and no recurrence of lethargy or weakness, for up to one-year post-surgery. El presente estudio tuvo como objetivo evaluar la evolución clínica de un caso de hipoglucemia como síndrome paraneoplásico en un canino con leiomioma de la pared gástrica. Fue estudiada una hembra entera canina de 10 años, de raza Fox terrier que acudió a consulta por aumento de tamaño del abdomen, letargia y debilidad. Fueron realizados estudios sanguíneos de hemograma (normal), perfil hepático (con aumento de la fosfatasa alcalina y GPT) y perfil renal (normal), Ca, P, K y Na normales, Glicemia de 35 mg dl-1. Al examen utrasonográfico se evidenció una estructura en región de epigastrio derecho e izquierdo con ecogenicidad mixta con mapeamiento Doppler interno positivo. En base a los hallazgos, se realizó la estabilización del paciente con 1 ml kg-1 de dextrosa al 50% para luego mantenerlo con solución isotónica de glucosa al 5%, pero al suspender su administración, se producía nuevamente la hipoglucemia. Se decidió ingresar a una laparotomía exploratoria de urgencia, siendo evaluada una masa circular de 14 x 9 x 8 cm de diámetro pedunculada comunicada con la curvatura mayor del estómago, sin adherencias y múltiples nodulaciones hepáticas. Se procedió a la extirpación de la masa y biopsia hepática, llamando la atención que, inmediatamente retirada la masa, la glucemia se tornó estable. El estudio histopatológico reportó un leiomioma gástrico. La evolución clínica posterior no reportó nuevas crisis de letargia ni debilidad, manteniéndose los niveles de glicemia normales hasta un año después del procedimiento. Universidad Nacional del Nordeste 2025-09-02 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://revistas.unne.edu.ar/index.php/vet/article/view/8606 10.30972/vet.3628606 Revista Veterinaria; Vol. 36 Núm. 2 (2025); 1-7 1669-6840 1668-4834 spa https://revistas.unne.edu.ar/index.php/vet/article/view/8606/8156 https://creativecommons.org/licenses/by-nc/4.0 |
| institution |
Universidad Nacional del Nordeste |
| institution_str |
I-48 |
| repository_str |
R-154 |
| container_title_str |
Revistas UNNE - Universidad Nacional del Noroeste (UNNE) |
| language |
Español |
| format |
Artículo revista |
| topic |
Canine leiomyoma hypoglycemia Canino leiomioma hipoglucemia |
| spellingShingle |
Canine leiomyoma hypoglycemia Canino leiomioma hipoglucemia Britez-Valinotti, C. E. Olivo, M. Unzain Meneses, J. A. Cardozo Areco, W. V. González-Vatteone, R. Hypoglycemia as paraneoplastic syndrome in a Fox terrier canine with leiomyoma in the gastric wall |
| topic_facet |
Canine leiomyoma hypoglycemia Canino leiomioma hipoglucemia |
| author |
Britez-Valinotti, C. E. Olivo, M. Unzain Meneses, J. A. Cardozo Areco, W. V. González-Vatteone, R. |
| author_facet |
Britez-Valinotti, C. E. Olivo, M. Unzain Meneses, J. A. Cardozo Areco, W. V. González-Vatteone, R. |
| author_sort |
Britez-Valinotti, C. E. |
| title |
Hypoglycemia as paraneoplastic syndrome in a Fox terrier canine with leiomyoma in the gastric wall |
| title_short |
Hypoglycemia as paraneoplastic syndrome in a Fox terrier canine with leiomyoma in the gastric wall |
| title_full |
Hypoglycemia as paraneoplastic syndrome in a Fox terrier canine with leiomyoma in the gastric wall |
| title_fullStr |
Hypoglycemia as paraneoplastic syndrome in a Fox terrier canine with leiomyoma in the gastric wall |
| title_full_unstemmed |
Hypoglycemia as paraneoplastic syndrome in a Fox terrier canine with leiomyoma in the gastric wall |
| title_sort |
hypoglycemia as paraneoplastic syndrome in a fox terrier canine with leiomyoma in the gastric wall |
| description |
The aim of this study was to evaluate the clinical progression of hypoglycemia as a paraneoplastic syndrome in a dog diagnosed with gastric wall leiomyoma. A 10-yeaxr-old female Fox Terrier was presented with abdominal distension, lethargy, and weakness. Hematological evaluation showed normal complete blood count and renal profile, while the liver profile revealed elevated alkaline phosphatase and GPT. Electrolytes (Ca, P, K, Na) were within normal limits, but blood glucose was markedly decreased (35 mg dl-1). Abdominal ultrasonography revealed a mixed-echogenic mass in the epigastric region with positive Doppler signal. The patient was stabilized with 1 ml kg-1 of 50% dextrose and maintained on 5% isotonic glucose solution; however, hypoglycemia recurred upon suspension of glucose therapy. An exploratory laparotomy was performed, revealing a pedunculated, circular mass (14 x 9 x 8 cm) attached to the greater curvature of the stomach, without adhesions, and multiple hepatic nodules. The mass was excised, and the liver biopsies were obtained. Remarkably, blood glucose levels stabilized immediately after tumor removal. Histopathology confirmed the diagnosis of gastric leiomyoma. The dog remained asymptomatic, with normal glycemia and no recurrence of lethargy or weakness, for up to one-year post-surgery. |
| publisher |
Universidad Nacional del Nordeste |
| publishDate |
2025 |
| url |
https://revistas.unne.edu.ar/index.php/vet/article/view/8606 |
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