Reference values for acetyl and butyrylcholinesterases in cattle under actual management conditions, hepatic and renal function by application of chlorpyrifos
ARTÍCULO PUBLICADO EN REVISTA EXTERNA. Chlorpyrifos is an anticholinesterase organophosphate insecticide widely used in Argentina in the production of food derived from animal, fruit and horticultural origin and is reported as a residue within these products. Local reference values for acetyl and...
| Autores principales: | , , , , , |
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| Formato: | Artículo Científico |
| Lenguaje: | Inglés |
| Publicado: |
Comité editorial Journal of Environmental Science and Health
2020
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| Materias: | |
| Acceso en línea: | http://repositorio.umaza.edu.ar//handle/00261/1834 https://pubmed.ncbi.nlm.nih.gov/29293401/ |
| Aporte de: |
| id |
I56-R16200261-1834 |
|---|---|
| record_format |
dspace |
| institution |
Universidad Juan Agustín MAZA |
| institution_str |
I-56 |
| repository_str |
R-162 |
| collection |
UMAZA Digital (Universidad MAZA - Mendoza) |
| language |
Inglés |
| orig_language_str_mv |
eng |
| topic |
Chlorpyrifos Cattle Chlolinesterases UHPLC Hematology Renal and liver function |
| spellingShingle |
Chlorpyrifos Cattle Chlolinesterases UHPLC Hematology Renal and liver function Ferré, Daniela Marisol Lentini, Valeria Roxana Romano, Raquel Ludueña, Héctor Ricardo Jotallán, Paola Jimena Gorla, Nora Bibiana María Reference values for acetyl and butyrylcholinesterases in cattle under actual management conditions, hepatic and renal function by application of chlorpyrifos |
| description |
ARTÍCULO PUBLICADO EN REVISTA EXTERNA. Chlorpyrifos is an anticholinesterase organophosphate insecticide widely used in Argentina in the
production of food derived from animal, fruit and horticultural origin and is reported as a residue within
these products. Local reference values for acetyl and butyrylcholinesterase were determined in Aberdeen
Angus bovine and cross bred cattle (n D 25), a requirement to be able to evaluate toxicity of commercial
organophosphate and carbamate formulations. The activity of cholinesterase enzymes presented an
overall mean of 2,183.00 § 485.6 IU L¡1 for erythrocyte acetylcholinesterase and 203.1 § 42.06 IU L¡1 for
plasma butyrylcholinesterase, which are used as reference values for meat steers within a system of
intensive production in a semi-arid region. The toxic potential of chlorpyrifos in steers of the same breeds
(n D 12) was assessed applying chlorpyrifos 15.00% Tipertox in a single therapeutic dose of 7.50 mg kg¡1
by topical route. Prior to application and then on day 1 and day 21 post-application, both blood
cholinesterases, serum chlorpyrifos concentration by ultra-high resolution liquid chromatography with
mass detector, analysis of blood counts, total proteins, liver enzymes, urea and creatinine were evaluated.
The mean plasma concentration of chlorpyrifos was 27.90 ug L¡1 at 24 h. The findings indicate that the
therapeutic treatment of castrated male bovines treated with chlorpyrifos, applied by pour-on according
to the manufacturer’s instructions, does not cause changes in the variables evaluated. Sitio de la revista: https://pubmed.ncbi.nlm.nih.gov/29293401/ |
| format |
Artículo Científico |
| author |
Ferré, Daniela Marisol Lentini, Valeria Roxana Romano, Raquel Ludueña, Héctor Ricardo Jotallán, Paola Jimena Gorla, Nora Bibiana María |
| author_facet |
Ferré, Daniela Marisol Lentini, Valeria Roxana Romano, Raquel Ludueña, Héctor Ricardo Jotallán, Paola Jimena Gorla, Nora Bibiana María |
| author_sort |
Ferré, Daniela Marisol |
| title |
Reference values for acetyl and butyrylcholinesterases in cattle under actual management conditions, hepatic and renal function by application of chlorpyrifos |
| title_short |
Reference values for acetyl and butyrylcholinesterases in cattle under actual management conditions, hepatic and renal function by application of chlorpyrifos |
| title_full |
Reference values for acetyl and butyrylcholinesterases in cattle under actual management conditions, hepatic and renal function by application of chlorpyrifos |
| title_fullStr |
Reference values for acetyl and butyrylcholinesterases in cattle under actual management conditions, hepatic and renal function by application of chlorpyrifos |
| title_full_unstemmed |
Reference values for acetyl and butyrylcholinesterases in cattle under actual management conditions, hepatic and renal function by application of chlorpyrifos |
| title_sort |
reference values for acetyl and butyrylcholinesterases in cattle under actual management conditions, hepatic and renal function by application of chlorpyrifos |
| publisher |
Comité editorial Journal of Environmental Science and Health |
| publishDate |
2020 |
| url |
http://repositorio.umaza.edu.ar//handle/00261/1834 https://pubmed.ncbi.nlm.nih.gov/29293401/ |
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