Tetrapyrrole biosynthesis from 4,5-dioxovaleric acid in Rhodopseudomonas spheroides

Porphyrin biosynthesis from 4,5-dioxovaleric acid was studied in cell suspensions of R. spheroides. The experiments show that 4,5-dioxovaleric acid is a far precursor of porphyrins through δ amino laevulinic acid formation in a transamination reaction involving also 1-alanine. It differs radically f...

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Autores principales: Couso, Roberto O., Locascio, Guillermo, Tigier, Horacio Alberto
Publicado: 1979
Materias:
alanine
aminolevulinic acid
porphyrin
animal experiment
dioxovaleric acid
dose response
drug industry
drug metabolism
drug response
in vitro study
rhodopseudomonas sphaeroides
spectrophotometry
tetrapyrrole
Alanine
Aminolevulinic Acid
Porphyrins
Rhodopseudomonas
Valerates
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00144754_v35_n2_p168_Couso
http://hdl.handle.net/20.500.12110/paper_00144754_v35_n2_p168_Couso
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id paper:paper_00144754_v35_n2_p168_Couso
record_format dspace
spelling paper:paper_00144754_v35_n2_p168_Couso2023-06-08T14:37:05Z Tetrapyrrole biosynthesis from 4,5-dioxovaleric acid in Rhodopseudomonas spheroides Couso, Roberto O. Locascio, Guillermo Tigier, Horacio Alberto alanine aminolevulinic acid porphyrin animal experiment dioxovaleric acid dose response drug industry drug metabolism drug response in vitro study rhodopseudomonas sphaeroides spectrophotometry tetrapyrrole Alanine Aminolevulinic Acid Porphyrins Rhodopseudomonas Valerates Porphyrin biosynthesis from 4,5-dioxovaleric acid was studied in cell suspensions of R. spheroides. The experiments show that 4,5-dioxovaleric acid is a far precursor of porphyrins through δ amino laevulinic acid formation in a transamination reaction involving also 1-alanine. It differs radically from the classical δ aminolaevulinic acid synthesis using glycine and succinyl CoA as substrates. © 1979 Birkhäuser Verlag. Fil:Couso, R. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Locascio, G.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Tigier, H.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 1979 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00144754_v35_n2_p168_Couso http://hdl.handle.net/20.500.12110/paper_00144754_v35_n2_p168_Couso
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic alanine
aminolevulinic acid
porphyrin
animal experiment
dioxovaleric acid
dose response
drug industry
drug metabolism
drug response
in vitro study
rhodopseudomonas sphaeroides
spectrophotometry
tetrapyrrole
Alanine
Aminolevulinic Acid
Porphyrins
Rhodopseudomonas
Valerates
spellingShingle alanine
aminolevulinic acid
porphyrin
animal experiment
dioxovaleric acid
dose response
drug industry
drug metabolism
drug response
in vitro study
rhodopseudomonas sphaeroides
spectrophotometry
tetrapyrrole
Alanine
Aminolevulinic Acid
Porphyrins
Rhodopseudomonas
Valerates
Couso, Roberto O.
Locascio, Guillermo
Tigier, Horacio Alberto
Tetrapyrrole biosynthesis from 4,5-dioxovaleric acid in Rhodopseudomonas spheroides
topic_facet alanine
aminolevulinic acid
porphyrin
animal experiment
dioxovaleric acid
dose response
drug industry
drug metabolism
drug response
in vitro study
rhodopseudomonas sphaeroides
spectrophotometry
tetrapyrrole
Alanine
Aminolevulinic Acid
Porphyrins
Rhodopseudomonas
Valerates
description Porphyrin biosynthesis from 4,5-dioxovaleric acid was studied in cell suspensions of R. spheroides. The experiments show that 4,5-dioxovaleric acid is a far precursor of porphyrins through δ amino laevulinic acid formation in a transamination reaction involving also 1-alanine. It differs radically from the classical δ aminolaevulinic acid synthesis using glycine and succinyl CoA as substrates. © 1979 Birkhäuser Verlag.
author Couso, Roberto O.
Locascio, Guillermo
Tigier, Horacio Alberto
author_facet Couso, Roberto O.
Locascio, Guillermo
Tigier, Horacio Alberto
author_sort Couso, Roberto O.
title Tetrapyrrole biosynthesis from 4,5-dioxovaleric acid in Rhodopseudomonas spheroides
title_short Tetrapyrrole biosynthesis from 4,5-dioxovaleric acid in Rhodopseudomonas spheroides
title_full Tetrapyrrole biosynthesis from 4,5-dioxovaleric acid in Rhodopseudomonas spheroides
title_fullStr Tetrapyrrole biosynthesis from 4,5-dioxovaleric acid in Rhodopseudomonas spheroides
title_full_unstemmed Tetrapyrrole biosynthesis from 4,5-dioxovaleric acid in Rhodopseudomonas spheroides
title_sort tetrapyrrole biosynthesis from 4,5-dioxovaleric acid in rhodopseudomonas spheroides
publishDate 1979
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00144754_v35_n2_p168_Couso
http://hdl.handle.net/20.500.12110/paper_00144754_v35_n2_p168_Couso
work_keys_str_mv AT cousorobertoo tetrapyrrolebiosynthesisfrom45dioxovalericacidinrhodopseudomonasspheroides
AT locascioguillermo tetrapyrrolebiosynthesisfrom45dioxovalericacidinrhodopseudomonasspheroides
AT tigierhoracioalberto tetrapyrrolebiosynthesisfrom45dioxovalericacidinrhodopseudomonasspheroides
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