Differential effects of methylphenidate and cocaine on GABA transmission in sensory thalamic nuclei

Methylphenidate (MPH) is widely used to treat children and adolescents diagnosed with attention deficit/hyperactivity disorder. Although MPH shares mechanistic similarities to cocaine, its effects on GABAergic transmission in sensory thalamic nuclei are unknown. Our objective was to compare cocaine...

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Detalles Bibliográficos
Publicado:	2013
Materias:	cocaine GABAergic transmission methylphenidate T-type calcium channels thalamic reticular nucleus ventrobasal thalamic nucleus 4 aminobutyric acid calcium channel T type calcium ion glutamate decarboxylase 67 4 aminobutyric acid release animal cell animal experiment animal model animal tissue article calcium current controlled study facilitation locomotion male mouse nerve cell inhibition nerve projection nonhuman postsynaptic membrane priority journal thalamus reticular nucleus thalamus ventral nucleus Western blotting Animals Blotting, Western Central Nervous System Stimulants Cocaine gamma-Aminobutyric Acid Male Methylphenidate Mice Mice, Inbred C57BL Patch-Clamp Techniques Synaptic Transmission Thalamic Nuclei Mus
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00223042_v124_n5_p602_Goitia http://hdl.handle.net/20.500.12110/paper_00223042_v124_n5_p602_Goitia
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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