A suitable method for a rapid estimation of sulphated positions in polysaccharides of pharmacological interest

Most polysaccharides of pharmacological interest bear sulphate substituents. Methylation analysis is still a powerful method for structural elucidation. The butyllithium-methyl iodide procedure, previously reported for neutral glycans, has been applied to sulphated polysaccharides. Results obtained...

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Autores principales: Kovensky, José Eduardo, Covian, Javier Agustín, Fernández Cirelli, Alicia
Publicado: 1990
Materias:
Carbohydrates
Sulfur Compounds > Structure
Heparan Sulphates
Heparin
Sulfated Glucans
Polysaccharides
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01448617_v12_n3_p307_Kovensky
http://hdl.handle.net/20.500.12110/paper_01448617_v12_n3_p307_Kovensky
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id paper:paper_01448617_v12_n3_p307_Kovensky
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spelling paper:paper_01448617_v12_n3_p307_Kovensky2023-06-08T15:12:00Z A suitable method for a rapid estimation of sulphated positions in polysaccharides of pharmacological interest Kovensky, José Eduardo Covian, Javier Agustín Fernández Cirelli, Alicia Carbohydrates Sulfur Compounds--Structure Heparan Sulphates Heparin Sulfated Glucans Polysaccharides Most polysaccharides of pharmacological interest bear sulphate substituents. Methylation analysis is still a powerful method for structural elucidation. The butyllithium-methyl iodide procedure, previously reported for neutral glycans, has been applied to sulphated polysaccharides. Results obtained with heparin, heparan sulphates and synthetic derivatives of natural β-(1 → 3)-glucans show that it is a convenient method for the rapid estimation of sulphated positions. © 1990. Fil:Kovensky, J. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Covián, J.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Fernandez Cirelli, A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 1990 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01448617_v12_n3_p307_Kovensky http://hdl.handle.net/20.500.12110/paper_01448617_v12_n3_p307_Kovensky
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Carbohydrates
Sulfur Compounds--Structure
Heparan Sulphates
Heparin
Sulfated Glucans
Polysaccharides
spellingShingle Carbohydrates
Sulfur Compounds--Structure
Heparan Sulphates
Heparin
Sulfated Glucans
Polysaccharides
Kovensky, José Eduardo
Covian, Javier Agustín
Fernández Cirelli, Alicia
A suitable method for a rapid estimation of sulphated positions in polysaccharides of pharmacological interest
topic_facet Carbohydrates
Sulfur Compounds--Structure
Heparan Sulphates
Heparin
Sulfated Glucans
Polysaccharides
description Most polysaccharides of pharmacological interest bear sulphate substituents. Methylation analysis is still a powerful method for structural elucidation. The butyllithium-methyl iodide procedure, previously reported for neutral glycans, has been applied to sulphated polysaccharides. Results obtained with heparin, heparan sulphates and synthetic derivatives of natural β-(1 → 3)-glucans show that it is a convenient method for the rapid estimation of sulphated positions. © 1990.
author Kovensky, José Eduardo
Covian, Javier Agustín
Fernández Cirelli, Alicia
author_facet Kovensky, José Eduardo
Covian, Javier Agustín
Fernández Cirelli, Alicia
author_sort Kovensky, José Eduardo
title A suitable method for a rapid estimation of sulphated positions in polysaccharides of pharmacological interest
title_short A suitable method for a rapid estimation of sulphated positions in polysaccharides of pharmacological interest
title_full A suitable method for a rapid estimation of sulphated positions in polysaccharides of pharmacological interest
title_fullStr A suitable method for a rapid estimation of sulphated positions in polysaccharides of pharmacological interest
title_full_unstemmed A suitable method for a rapid estimation of sulphated positions in polysaccharides of pharmacological interest
title_sort suitable method for a rapid estimation of sulphated positions in polysaccharides of pharmacological interest
publishDate 1990
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01448617_v12_n3_p307_Kovensky
http://hdl.handle.net/20.500.12110/paper_01448617_v12_n3_p307_Kovensky
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