Synthesis of |21‐14C|‐3β‐hydroxy‐5β‐pregnan‐20‐one and |21‐14C|‐5β‐cholestan‐3β‐ol

|21‐14C|‐3β‐Hydroxy‐5β‐pregnan‐20‐one was synthesised from 3β‐acetoxy‐5β‐androstan‐17β‐carboxylic acid chloride and |14C2|dimethyl‐cadmium. Reaction of the labelled product with isohexyl bromide yielded, after dehydration and catalytic hydrogenation, |21‐14C|‐5β‐cholestan‐3β‐ol (|21‐14C|‐coprostanol...

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Detalles Bibliográficos
Autores principales:	Garraffo, Hugo Martín, Deluca, Mónica Eva, Seldes, Alicia Marta
Publicado:	1985
Materias:	Synthesis \|21‐14C\|‐3β‐Hydroxy‐5β‐pregnan‐20‐one \|21‐14C\|‐Coprostanol radioisotope 5beta pregnan 3beta ol 20 one c 14 coprosterol c 14 drug analysis drug identification drug synthesis mass spectrometry nonhuman nuclear magnetic resonance priority journal proton nuclear magnetic resonance theoretical study
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03624803_v22_n7_p673_Garraffo http://hdl.handle.net/20.500.12110/paper_03624803_v22_n7_p673_Garraffo
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_03624803_v22_n7_p673_Garraffo
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spelling	paper:paper_03624803_v22_n7_p673_Garraffo2023-06-08T15:35:08Z Synthesis of \|21‐14C\|‐3β‐hydroxy‐5β‐pregnan‐20‐one and \|21‐14C\|‐5β‐cholestan‐3β‐ol Garraffo, Hugo Martín Deluca, Mónica Eva Seldes, Alicia Marta Synthesis \|21‐14C\|‐3β‐Hydroxy‐5β‐pregnan‐20‐one \|21‐14C\|‐Coprostanol radioisotope 5beta pregnan 3beta ol 20 one c 14 coprosterol c 14 drug analysis drug identification drug synthesis mass spectrometry nonhuman nuclear magnetic resonance priority journal proton nuclear magnetic resonance theoretical study \|21‐14C\|‐3β‐Hydroxy‐5β‐pregnan‐20‐one was synthesised from 3β‐acetoxy‐5β‐androstan‐17β‐carboxylic acid chloride and \|14C2\|dimethyl‐cadmium. Reaction of the labelled product with isohexyl bromide yielded, after dehydration and catalytic hydrogenation, \|21‐14C\|‐5β‐cholestan‐3β‐ol (\|21‐14C\|‐coprostanol). Copyright © 1985 John Wiley & Sons, Ltd. Fil:Garraffo, H.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Deluca, M.E. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Seldes, A.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 1985 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03624803_v22_n7_p673_Garraffo http://hdl.handle.net/20.500.12110/paper_03624803_v22_n7_p673_Garraffo
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Synthesis \|21‐14C\|‐3β‐Hydroxy‐5β‐pregnan‐20‐one \|21‐14C\|‐Coprostanol radioisotope 5beta pregnan 3beta ol 20 one c 14 coprosterol c 14 drug analysis drug identification drug synthesis mass spectrometry nonhuman nuclear magnetic resonance priority journal proton nuclear magnetic resonance theoretical study
spellingShingle	Synthesis \|21‐14C\|‐3β‐Hydroxy‐5β‐pregnan‐20‐one \|21‐14C\|‐Coprostanol radioisotope 5beta pregnan 3beta ol 20 one c 14 coprosterol c 14 drug analysis drug identification drug synthesis mass spectrometry nonhuman nuclear magnetic resonance priority journal proton nuclear magnetic resonance theoretical study Garraffo, Hugo Martín Deluca, Mónica Eva Seldes, Alicia Marta Synthesis of \|21‐14C\|‐3β‐hydroxy‐5β‐pregnan‐20‐one and \|21‐14C\|‐5β‐cholestan‐3β‐ol
topic_facet	Synthesis \|21‐14C\|‐3β‐Hydroxy‐5β‐pregnan‐20‐one \|21‐14C\|‐Coprostanol radioisotope 5beta pregnan 3beta ol 20 one c 14 coprosterol c 14 drug analysis drug identification drug synthesis mass spectrometry nonhuman nuclear magnetic resonance priority journal proton nuclear magnetic resonance theoretical study
description	\|21‐14C\|‐3β‐Hydroxy‐5β‐pregnan‐20‐one was synthesised from 3β‐acetoxy‐5β‐androstan‐17β‐carboxylic acid chloride and \|14C2\|dimethyl‐cadmium. Reaction of the labelled product with isohexyl bromide yielded, after dehydration and catalytic hydrogenation, \|21‐14C\|‐5β‐cholestan‐3β‐ol (\|21‐14C\|‐coprostanol). Copyright © 1985 John Wiley & Sons, Ltd.
author	Garraffo, Hugo Martín Deluca, Mónica Eva Seldes, Alicia Marta
author_facet	Garraffo, Hugo Martín Deluca, Mónica Eva Seldes, Alicia Marta
author_sort	Garraffo, Hugo Martín
title	Synthesis of \|21‐14C\|‐3β‐hydroxy‐5β‐pregnan‐20‐one and \|21‐14C\|‐5β‐cholestan‐3β‐ol
title_short	Synthesis of \|21‐14C\|‐3β‐hydroxy‐5β‐pregnan‐20‐one and \|21‐14C\|‐5β‐cholestan‐3β‐ol
title_full	Synthesis of \|21‐14C\|‐3β‐hydroxy‐5β‐pregnan‐20‐one and \|21‐14C\|‐5β‐cholestan‐3β‐ol
title_fullStr	Synthesis of \|21‐14C\|‐3β‐hydroxy‐5β‐pregnan‐20‐one and \|21‐14C\|‐5β‐cholestan‐3β‐ol
title_full_unstemmed	Synthesis of \|21‐14C\|‐3β‐hydroxy‐5β‐pregnan‐20‐one and \|21‐14C\|‐5β‐cholestan‐3β‐ol
title_sort	synthesis of \|21‐14c\|‐3β‐hydroxy‐5β‐pregnan‐20‐one and \|21‐14c\|‐5β‐cholestan‐3β‐ol
publishDate	1985
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03624803_v22_n7_p673_Garraffo http://hdl.handle.net/20.500.12110/paper_03624803_v22_n7_p673_Garraffo
work_keys_str_mv	AT garraffohugomartin synthesisof2114c3bhydroxy5bpregnan20oneand2114c5bcholestan3bol AT delucamonicaeva synthesisof2114c3bhydroxy5bpregnan20oneand2114c5bcholestan3bol AT seldesaliciamarta synthesisof2114c3bhydroxy5bpregnan20oneand2114c5bcholestan3bol
_version_	1768543660210651136

Synthesis of |21‐14C|‐3β‐hydroxy‐5β‐pregnan‐20‐one and |21‐14C|‐5β‐cholestan‐3β‐ol

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