Maternal chronic stress induces premature telencephalic vesicles development
Exposure to physical or psychological stress causes brain damage ranging from minimal behavioural alterations to different neurodegeneration degrees implying the overproduction of oxidative-nitrosative compounds, apoptosis and cell proliferation. In the present investigation, we have analysed the ef...
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2006
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_07179367_v24_n4_p525_Mugnaini http://hdl.handle.net/20.500.12110/paper_07179367_v24_n4_p525_Mugnaini |
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paper:paper_07179367_v24_n4_p525_Mugnaini2023-06-08T15:43:05Z Maternal chronic stress induces premature telencephalic vesicles development Chronic stress Morphometric analysis Rats Telencephalic vesicle Exposure to physical or psychological stress causes brain damage ranging from minimal behavioural alterations to different neurodegeneration degrees implying the overproduction of oxidative-nitrosative compounds, apoptosis and cell proliferation. In the present investigation, we have analysed the effect of the chronic stress by immobilisation applied to pregnant rats over the forebrain development of the embryos. The morphometric analyses showed an accelerated evagination of the telencephalic vesicles in 12 days old fetus from stressed mothers. The forebrain perimeter and the thickness showed significative differences in relation to age-matched controls. This stress effect seemed reversible during subsequent gestational stages. This is the first work showing a transient acceleration in the development induced by the gestational stress. Our model provides a new tool for studying the effect of the stress on the development. © 2007 Sociedad Chilena de Anatom•br>. 2006 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_07179367_v24_n4_p525_Mugnaini http://hdl.handle.net/20.500.12110/paper_07179367_v24_n4_p525_Mugnaini |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Chronic stress Morphometric analysis Rats Telencephalic vesicle |
| spellingShingle |
Chronic stress Morphometric analysis Rats Telencephalic vesicle Maternal chronic stress induces premature telencephalic vesicles development |
| topic_facet |
Chronic stress Morphometric analysis Rats Telencephalic vesicle |
| description |
Exposure to physical or psychological stress causes brain damage ranging from minimal behavioural alterations to different neurodegeneration degrees implying the overproduction of oxidative-nitrosative compounds, apoptosis and cell proliferation. In the present investigation, we have analysed the effect of the chronic stress by immobilisation applied to pregnant rats over the forebrain development of the embryos. The morphometric analyses showed an accelerated evagination of the telencephalic vesicles in 12 days old fetus from stressed mothers. The forebrain perimeter and the thickness showed significative differences in relation to age-matched controls. This stress effect seemed reversible during subsequent gestational stages. This is the first work showing a transient acceleration in the development induced by the gestational stress. Our model provides a new tool for studying the effect of the stress on the development. © 2007 Sociedad Chilena de Anatom•br>. |
| title |
Maternal chronic stress induces premature telencephalic vesicles development |
| title_short |
Maternal chronic stress induces premature telencephalic vesicles development |
| title_full |
Maternal chronic stress induces premature telencephalic vesicles development |
| title_fullStr |
Maternal chronic stress induces premature telencephalic vesicles development |
| title_full_unstemmed |
Maternal chronic stress induces premature telencephalic vesicles development |
| title_sort |
maternal chronic stress induces premature telencephalic vesicles development |
| publishDate |
2006 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_07179367_v24_n4_p525_Mugnaini http://hdl.handle.net/20.500.12110/paper_07179367_v24_n4_p525_Mugnaini |
| _version_ |
1768543950702903296 |