Positive regulation of raphe serotonin neurons by serotonin 2B receptors

Serotonin is a neurotransmitter involved in many psychiatric diseases. In humans, a lack of 5-HT 2B receptors is associated with serotonin-dependent phenotypes, including impulsivity and suicidality. A lack of 5-HT 2B receptors in mice eliminates the effects of molecules that directly target seroton...

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Detalles Bibliográficos
Publicado:	2018
Materias:	1 [5 (2 thienylmethoxy) 3 indolyl] 2 propanamine 4 iodo 2,5 dimethoxyamphetamine autoreceptor fluoxetine midomafetamine serotonin 1A receptor serotonin 2B receptor 1-(5-(2-thenyloxy)-1H-indol-3-yl)propan-2-amine 2 dipropylamino 8 hydroxytetralin 3,4 methylenedioxyamphetamine 4-iodo-2,5-dimethoxyphenylisopropylamine amphetamine derivative Fev protein, mouse indole derivative serotonin 2 agonist thiophene derivative transcription factor animal behavior animal cell animal experiment animal tissue Article brain electrophysiology brain slice brain synaptosome comparative study controlled study dorsal raphe nucleus ex vivo study firing rate forced swim test gene overexpression head twitch hypothermia immobility time locomotion male mouse nerve cell excitability nerve stimulation nonhuman prepulse inhibition priority journal regulatory mechanism serotoninergic nerve cell subgranular zone action potential animal body temperature central nervous system sensitization drug effect female genetics knockout mouse nervous system development physiology raphe nucleus transgenic mouse 3,4-Methylenedioxyamphetamine 8-Hydroxy-2-(di-n-propylamino)tetralin Action Potentials Amphetamines Animals Body Temperature Central Nervous System Sensitization Female Fluoxetine Indoles Male Mice Mice, Knockout Mice, Transgenic Neurogenesis Prepulse Inhibition Raphe Nuclei Receptor, Serotonin, 5-HT2B Serotonergic Neurons Serotonin 5-HT2 Receptor Agonists Thiophenes Transcription Factors
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0893133X_v43_n7_p1623_Belmer http://hdl.handle.net/20.500.12110/paper_0893133X_v43_n7_p1623_Belmer
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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