Virucidal activity in aqueous extracts obtained from Cedrela tubiflora leaves
Crude extracts obtained from leaves of Cedrela tubiflora (CT) (Meliaceae family) show antiviral and virucidal effects against several viruses. Herpes simplex, pseudorabies and vesicular stomatitis viruses were extremely susceptible and a reduction of 3–5 log in infectivity occurred after 15 min of d...
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1991
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Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0951418X_v5_n6_p250_Cordoba http://hdl.handle.net/20.500.12110/paper_0951418X_v5_n6_p250_Cordoba |
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paper:paper_0951418X_v5_n6_p250_Cordoba2023-06-08T15:54:56Z Virucidal activity in aqueous extracts obtained from Cedrela tubiflora leaves Coto, Celia Esther Damonte, Elsa Beatriz Cedrela tubiflora herpes‐virus Meliaceae plant antiviral vesicular stomatitis virus virucidal activity cedrela tubiflora extract plant extract unclassified drug animal cell antiviral activity article controlled study cytotoxicity herpes simplex virus 1 nonhuman plant leaf poliomyelitis virus pseudorabies herpetovirus vero cell vesicular stomatitis virus Animalia Arenavirus Cedrela Cedrela tubiflora Herpes herpetovirus Human herpesvirus 1 Meliaceae Poliovirus Suid herpesvirus 1 Vesicular stomatitis virus Crude extracts obtained from leaves of Cedrela tubiflora (CT) (Meliaceae family) show antiviral and virucidal effects against several viruses. Herpes simplex, pseudorabies and vesicular stomatitis viruses were extremely susceptible and a reduction of 3–5 log in infectivity occurred after 15 min of direct incubation with the plant extract. By contrast, poliovirus and the Tacaribe arenavirus are inhibited intracellularly. The inhibitory action is dose dependent and no cytotoxic effects were detected on Vero cells after 2 days of CT treatment. Copyright © 1991 John Wiley & Sons, Ltd. Fil:Coto, C.E. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Damonte, E.B. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 1991 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0951418X_v5_n6_p250_Cordoba http://hdl.handle.net/20.500.12110/paper_0951418X_v5_n6_p250_Cordoba |
institution |
Universidad de Buenos Aires |
institution_str |
I-28 |
repository_str |
R-134 |
collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
topic |
Cedrela tubiflora herpes‐virus Meliaceae plant antiviral vesicular stomatitis virus virucidal activity cedrela tubiflora extract plant extract unclassified drug animal cell antiviral activity article controlled study cytotoxicity herpes simplex virus 1 nonhuman plant leaf poliomyelitis virus pseudorabies herpetovirus vero cell vesicular stomatitis virus Animalia Arenavirus Cedrela Cedrela tubiflora Herpes herpetovirus Human herpesvirus 1 Meliaceae Poliovirus Suid herpesvirus 1 Vesicular stomatitis virus |
spellingShingle |
Cedrela tubiflora herpes‐virus Meliaceae plant antiviral vesicular stomatitis virus virucidal activity cedrela tubiflora extract plant extract unclassified drug animal cell antiviral activity article controlled study cytotoxicity herpes simplex virus 1 nonhuman plant leaf poliomyelitis virus pseudorabies herpetovirus vero cell vesicular stomatitis virus Animalia Arenavirus Cedrela Cedrela tubiflora Herpes herpetovirus Human herpesvirus 1 Meliaceae Poliovirus Suid herpesvirus 1 Vesicular stomatitis virus Coto, Celia Esther Damonte, Elsa Beatriz Virucidal activity in aqueous extracts obtained from Cedrela tubiflora leaves |
topic_facet |
Cedrela tubiflora herpes‐virus Meliaceae plant antiviral vesicular stomatitis virus virucidal activity cedrela tubiflora extract plant extract unclassified drug animal cell antiviral activity article controlled study cytotoxicity herpes simplex virus 1 nonhuman plant leaf poliomyelitis virus pseudorabies herpetovirus vero cell vesicular stomatitis virus Animalia Arenavirus Cedrela Cedrela tubiflora Herpes herpetovirus Human herpesvirus 1 Meliaceae Poliovirus Suid herpesvirus 1 Vesicular stomatitis virus |
description |
Crude extracts obtained from leaves of Cedrela tubiflora (CT) (Meliaceae family) show antiviral and virucidal effects against several viruses. Herpes simplex, pseudorabies and vesicular stomatitis viruses were extremely susceptible and a reduction of 3–5 log in infectivity occurred after 15 min of direct incubation with the plant extract. By contrast, poliovirus and the Tacaribe arenavirus are inhibited intracellularly. The inhibitory action is dose dependent and no cytotoxic effects were detected on Vero cells after 2 days of CT treatment. Copyright © 1991 John Wiley & Sons, Ltd. |
author |
Coto, Celia Esther Damonte, Elsa Beatriz |
author_facet |
Coto, Celia Esther Damonte, Elsa Beatriz |
author_sort |
Coto, Celia Esther |
title |
Virucidal activity in aqueous extracts obtained from Cedrela tubiflora leaves |
title_short |
Virucidal activity in aqueous extracts obtained from Cedrela tubiflora leaves |
title_full |
Virucidal activity in aqueous extracts obtained from Cedrela tubiflora leaves |
title_fullStr |
Virucidal activity in aqueous extracts obtained from Cedrela tubiflora leaves |
title_full_unstemmed |
Virucidal activity in aqueous extracts obtained from Cedrela tubiflora leaves |
title_sort |
virucidal activity in aqueous extracts obtained from cedrela tubiflora leaves |
publishDate |
1991 |
url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0951418X_v5_n6_p250_Cordoba http://hdl.handle.net/20.500.12110/paper_0951418X_v5_n6_p250_Cordoba |
work_keys_str_mv |
AT cotoceliaesther virucidalactivityinaqueousextractsobtainedfromcedrelatubifloraleaves AT damonteelsabeatriz virucidalactivityinaqueousextractsobtainedfromcedrelatubifloraleaves |
_version_ |
1768545471943409664 |