Synthesis and biological activivity of juvenele hormone analogues (JHA) for Trypanosoma cruzi

Several derivatives of geraniol, geranylacetone, and farnesol bearing carbonate and thiolcarbonate functional groups as well as several derivatives of 4-phenoxyphenol were synthesized and tested for their respective biological activity as growth inhibitors for Trypanosoma cruzi, and for inhibition o...

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Autores principales: Rodríguez, Juan Bautista, Gros, Eduardo Gervasio, Stoka, Ángel de la Merced
Publicado: 1991
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Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0960894X_v1_n12_p679_Rodriguez
http://hdl.handle.net/20.500.12110/paper_0960894X_v1_n12_p679_Rodriguez
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spelling paper:paper_0960894X_v1_n12_p679_Rodriguez2023-06-08T15:57:50Z Synthesis and biological activivity of juvenele hormone analogues (JHA) for Trypanosoma cruzi Rodríguez, Juan Bautista Gros, Eduardo Gervasio Stoka, Ángel de la Merced juvenile hormone derivative methoprene article cytotoxicity dna synthesis nonhuman trypanosoma cruzi Several derivatives of geraniol, geranylacetone, and farnesol bearing carbonate and thiolcarbonate functional groups as well as several derivatives of 4-phenoxyphenol were synthesized and tested for their respective biological activity as growth inhibitors for Trypanosoma cruzi, and for inhibition of tritium-labelled thymidine incorporation in T. cruzi cells. The results indicated that some JHA showed important activity against the development of the cells. © 1991. Fil:Rodriguez, J.B. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Gros, E.G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Stoka, A.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 1991 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0960894X_v1_n12_p679_Rodriguez http://hdl.handle.net/20.500.12110/paper_0960894X_v1_n12_p679_Rodriguez
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic juvenile hormone derivative
methoprene
article
cytotoxicity
dna synthesis
nonhuman
trypanosoma cruzi
spellingShingle juvenile hormone derivative
methoprene
article
cytotoxicity
dna synthesis
nonhuman
trypanosoma cruzi
Rodríguez, Juan Bautista
Gros, Eduardo Gervasio
Stoka, Ángel de la Merced
Synthesis and biological activivity of juvenele hormone analogues (JHA) for Trypanosoma cruzi
topic_facet juvenile hormone derivative
methoprene
article
cytotoxicity
dna synthesis
nonhuman
trypanosoma cruzi
description Several derivatives of geraniol, geranylacetone, and farnesol bearing carbonate and thiolcarbonate functional groups as well as several derivatives of 4-phenoxyphenol were synthesized and tested for their respective biological activity as growth inhibitors for Trypanosoma cruzi, and for inhibition of tritium-labelled thymidine incorporation in T. cruzi cells. The results indicated that some JHA showed important activity against the development of the cells. © 1991.
author Rodríguez, Juan Bautista
Gros, Eduardo Gervasio
Stoka, Ángel de la Merced
author_facet Rodríguez, Juan Bautista
Gros, Eduardo Gervasio
Stoka, Ángel de la Merced
author_sort Rodríguez, Juan Bautista
title Synthesis and biological activivity of juvenele hormone analogues (JHA) for Trypanosoma cruzi
title_short Synthesis and biological activivity of juvenele hormone analogues (JHA) for Trypanosoma cruzi
title_full Synthesis and biological activivity of juvenele hormone analogues (JHA) for Trypanosoma cruzi
title_fullStr Synthesis and biological activivity of juvenele hormone analogues (JHA) for Trypanosoma cruzi
title_full_unstemmed Synthesis and biological activivity of juvenele hormone analogues (JHA) for Trypanosoma cruzi
title_sort synthesis and biological activivity of juvenele hormone analogues (jha) for trypanosoma cruzi
publishDate 1991
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0960894X_v1_n12_p679_Rodriguez
http://hdl.handle.net/20.500.12110/paper_0960894X_v1_n12_p679_Rodriguez
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