Antioxidant and cardioprotective effects of Ilex brasiliensis: A comparative study with Ilex paraguariensis (yerba mate)
Our objective was to compare the antioxidant properties and cardiovascular effects in ischemia-reperfusion of leaves aqueous extracts of Ilex brasiliensis (B) and Ilex paraguariensis (P). In vitro systems were used to assess the antioxidant properties of the extracts. Isolated rat hearts were treate...
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2009
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09639969_v42_n10_p1403_Schinella http://hdl.handle.net/20.500.12110/paper_09639969_v42_n10_p1403_Schinella |
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paper:paper_09639969_v42_n10_p1403_Schinella2023-06-08T15:58:25Z Antioxidant and cardioprotective effects of Ilex brasiliensis: A comparative study with Ilex paraguariensis (yerba mate) Antioxidant capacity GSH Ilex brasiliensis Ilex paraguariensis Ischemia Reperfusion TBARS Antioxidant capacity GSH Ilex brasiliensis Ilex paraguariensis Ischemia Reperfusion TBARS Ketones Organic acids Phenols Solvent extraction Croton ovalifolius Ilex Ilex brasiliensis Ilex paraguariensis Rattus Our objective was to compare the antioxidant properties and cardiovascular effects in ischemia-reperfusion of leaves aqueous extracts of Ilex brasiliensis (B) and Ilex paraguariensis (P). In vitro systems were used to assess the antioxidant properties of the extracts. Isolated rat hearts were treated with both extracts before ischemia and myocardial function was assessed. Thiobarbituric acid reactive substances (TBARS) concentration and reduced glutathione (GSH) were also measured. B extract showed higher total phenols and ascorbic acid contents and a higher scavenging activity of peroxynitrite and ferric reducing antioxidant power (FRAP) than P extract. Postischemic systolic and diastolic functions were improved after B and P treatment. Both extracts decreased TBARS and preserved GSH content. The present study demonstrates that an aqueous extract of I. brasiliensis, similar to I. paraguariensis, protects the myocardium against ischemia-reperfusion injury and attenuates oxidative damage. These effects may be attributed to the potent antioxidant properties of the extract. © 2009 Elsevier Ltd. All rights reserved. 2009 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09639969_v42_n10_p1403_Schinella http://hdl.handle.net/20.500.12110/paper_09639969_v42_n10_p1403_Schinella |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Antioxidant capacity GSH Ilex brasiliensis Ilex paraguariensis Ischemia Reperfusion TBARS Antioxidant capacity GSH Ilex brasiliensis Ilex paraguariensis Ischemia Reperfusion TBARS Ketones Organic acids Phenols Solvent extraction Croton ovalifolius Ilex Ilex brasiliensis Ilex paraguariensis Rattus |
| spellingShingle |
Antioxidant capacity GSH Ilex brasiliensis Ilex paraguariensis Ischemia Reperfusion TBARS Antioxidant capacity GSH Ilex brasiliensis Ilex paraguariensis Ischemia Reperfusion TBARS Ketones Organic acids Phenols Solvent extraction Croton ovalifolius Ilex Ilex brasiliensis Ilex paraguariensis Rattus Antioxidant and cardioprotective effects of Ilex brasiliensis: A comparative study with Ilex paraguariensis (yerba mate) |
| topic_facet |
Antioxidant capacity GSH Ilex brasiliensis Ilex paraguariensis Ischemia Reperfusion TBARS Antioxidant capacity GSH Ilex brasiliensis Ilex paraguariensis Ischemia Reperfusion TBARS Ketones Organic acids Phenols Solvent extraction Croton ovalifolius Ilex Ilex brasiliensis Ilex paraguariensis Rattus |
| description |
Our objective was to compare the antioxidant properties and cardiovascular effects in ischemia-reperfusion of leaves aqueous extracts of Ilex brasiliensis (B) and Ilex paraguariensis (P). In vitro systems were used to assess the antioxidant properties of the extracts. Isolated rat hearts were treated with both extracts before ischemia and myocardial function was assessed. Thiobarbituric acid reactive substances (TBARS) concentration and reduced glutathione (GSH) were also measured. B extract showed higher total phenols and ascorbic acid contents and a higher scavenging activity of peroxynitrite and ferric reducing antioxidant power (FRAP) than P extract. Postischemic systolic and diastolic functions were improved after B and P treatment. Both extracts decreased TBARS and preserved GSH content. The present study demonstrates that an aqueous extract of I. brasiliensis, similar to I. paraguariensis, protects the myocardium against ischemia-reperfusion injury and attenuates oxidative damage. These effects may be attributed to the potent antioxidant properties of the extract. © 2009 Elsevier Ltd. All rights reserved. |
| title |
Antioxidant and cardioprotective effects of Ilex brasiliensis: A comparative study with Ilex paraguariensis (yerba mate) |
| title_short |
Antioxidant and cardioprotective effects of Ilex brasiliensis: A comparative study with Ilex paraguariensis (yerba mate) |
| title_full |
Antioxidant and cardioprotective effects of Ilex brasiliensis: A comparative study with Ilex paraguariensis (yerba mate) |
| title_fullStr |
Antioxidant and cardioprotective effects of Ilex brasiliensis: A comparative study with Ilex paraguariensis (yerba mate) |
| title_full_unstemmed |
Antioxidant and cardioprotective effects of Ilex brasiliensis: A comparative study with Ilex paraguariensis (yerba mate) |
| title_sort |
antioxidant and cardioprotective effects of ilex brasiliensis: a comparative study with ilex paraguariensis (yerba mate) |
| publishDate |
2009 |
| url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09639969_v42_n10_p1403_Schinella http://hdl.handle.net/20.500.12110/paper_09639969_v42_n10_p1403_Schinella |
| _version_ |
1768542373604753408 |