Steroidogenesis in immature chicken ovary. Hormonal stimulation of adenylyl cyclase system by luteinizing hormone and β-adrenergic agonists

The presence of a hormonally responsive adenylyl cyclase in the immature chicken ovary was investigated. We found that there was a highly significant difference (P< 0. 05) between basal and LH and catecholamine activatable activities. In addition, the basal activity was stimulated by NaF, forskol...

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Autores principales:	González, Claudia Beatriz, Cantore de Ezcurra, María Leonor
Publicado:	1994
Materias:	adenylate cyclase adrenalin beta adrenergic receptor stimulating agent catecholamine cyclic amp fluoride sodium forskolin guanylylimidodiphosphate isoprenaline luteinizing hormone progesterone propranolol animal tissue article chicken dose response drug antagonism drug mixture drug potentiation enzyme activation enzyme activity enzyme inhibition hormonal regulation nonhuman ovary development progesterone synthesis second messenger signal transduction steroidogenesis tissue homogenate Adenylate Cyclase Animal Chickens Cyclic AMP Enzyme Activation Epinephrine Female Forskolin Guanylyl Imidodiphosphate Isoproterenol Luteinizing Hormone Ovary Progesterone Propranolol Sodium Fluoride Support, Non-U.S. Gov't
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_10656995_v18_n2_p103_Gonzalez http://hdl.handle.net/20.500.12110/paper_10656995_v18_n2_p103_Gonzalez
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_10656995_v18_n2_p103_Gonzalez
record_format	dspace
spelling	paper:paper_10656995_v18_n2_p103_Gonzalez2023-06-08T16:04:14Z Steroidogenesis in immature chicken ovary. Hormonal stimulation of adenylyl cyclase system by luteinizing hormone and β-adrenergic agonists González, Claudia Beatriz Cantore de Ezcurra, María Leonor adenylate cyclase adrenalin beta adrenergic receptor stimulating agent catecholamine cyclic amp fluoride sodium forskolin guanylylimidodiphosphate isoprenaline luteinizing hormone progesterone propranolol animal tissue article chicken dose response drug antagonism drug mixture drug potentiation enzyme activation enzyme activity enzyme inhibition hormonal regulation nonhuman ovary development progesterone synthesis second messenger signal transduction steroidogenesis tissue homogenate Adenylate Cyclase Animal Chickens Cyclic AMP Enzyme Activation Epinephrine Female Forskolin Guanylyl Imidodiphosphate Isoproterenol Luteinizing Hormone Ovary Progesterone Propranolol Sodium Fluoride Support, Non-U.S. Gov't The presence of a hormonally responsive adenylyl cyclase in the immature chicken ovary was investigated. We found that there was a highly significant difference (P< 0. 05) between basal and LH and catecholamine activatable activities. In addition, the basal activity was stimulated by NaF, forskolin and the non-hydrolyzable GTP analogue guanosine-5′-(β, gamma;-imido)-triphosphate (GMPP(NH)P. The action of catecholamines on cyclic AMP and progesterone production was also investigated and compared to that of LH. The stimulatory effect of isoproterenol on cyclic AMP and progesterone production was significantly higher (P< 0.05) than that of LH. The β-adrenergic antagonist propranolol caused complete inhibition of the stimulatory action of catecholamines. Progesterone accumulation induced by LH or isoproterenol was synergistically augmentated by the simultaneous presence of both inducers. © 1994 Academic Press. All rights reserved. Fil:Gonzalez, C.B. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Cantore, M.L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 1994 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_10656995_v18_n2_p103_Gonzalez http://hdl.handle.net/20.500.12110/paper_10656995_v18_n2_p103_Gonzalez
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	adenylate cyclase adrenalin beta adrenergic receptor stimulating agent catecholamine cyclic amp fluoride sodium forskolin guanylylimidodiphosphate isoprenaline luteinizing hormone progesterone propranolol animal tissue article chicken dose response drug antagonism drug mixture drug potentiation enzyme activation enzyme activity enzyme inhibition hormonal regulation nonhuman ovary development progesterone synthesis second messenger signal transduction steroidogenesis tissue homogenate Adenylate Cyclase Animal Chickens Cyclic AMP Enzyme Activation Epinephrine Female Forskolin Guanylyl Imidodiphosphate Isoproterenol Luteinizing Hormone Ovary Progesterone Propranolol Sodium Fluoride Support, Non-U.S. Gov't
spellingShingle	adenylate cyclase adrenalin beta adrenergic receptor stimulating agent catecholamine cyclic amp fluoride sodium forskolin guanylylimidodiphosphate isoprenaline luteinizing hormone progesterone propranolol animal tissue article chicken dose response drug antagonism drug mixture drug potentiation enzyme activation enzyme activity enzyme inhibition hormonal regulation nonhuman ovary development progesterone synthesis second messenger signal transduction steroidogenesis tissue homogenate Adenylate Cyclase Animal Chickens Cyclic AMP Enzyme Activation Epinephrine Female Forskolin Guanylyl Imidodiphosphate Isoproterenol Luteinizing Hormone Ovary Progesterone Propranolol Sodium Fluoride Support, Non-U.S. Gov't González, Claudia Beatriz Cantore de Ezcurra, María Leonor Steroidogenesis in immature chicken ovary. Hormonal stimulation of adenylyl cyclase system by luteinizing hormone and β-adrenergic agonists
topic_facet	adenylate cyclase adrenalin beta adrenergic receptor stimulating agent catecholamine cyclic amp fluoride sodium forskolin guanylylimidodiphosphate isoprenaline luteinizing hormone progesterone propranolol animal tissue article chicken dose response drug antagonism drug mixture drug potentiation enzyme activation enzyme activity enzyme inhibition hormonal regulation nonhuman ovary development progesterone synthesis second messenger signal transduction steroidogenesis tissue homogenate Adenylate Cyclase Animal Chickens Cyclic AMP Enzyme Activation Epinephrine Female Forskolin Guanylyl Imidodiphosphate Isoproterenol Luteinizing Hormone Ovary Progesterone Propranolol Sodium Fluoride Support, Non-U.S. Gov't
description	The presence of a hormonally responsive adenylyl cyclase in the immature chicken ovary was investigated. We found that there was a highly significant difference (P< 0. 05) between basal and LH and catecholamine activatable activities. In addition, the basal activity was stimulated by NaF, forskolin and the non-hydrolyzable GTP analogue guanosine-5′-(β, gamma;-imido)-triphosphate (GMPP(NH)P. The action of catecholamines on cyclic AMP and progesterone production was also investigated and compared to that of LH. The stimulatory effect of isoproterenol on cyclic AMP and progesterone production was significantly higher (P< 0.05) than that of LH. The β-adrenergic antagonist propranolol caused complete inhibition of the stimulatory action of catecholamines. Progesterone accumulation induced by LH or isoproterenol was synergistically augmentated by the simultaneous presence of both inducers. © 1994 Academic Press. All rights reserved.
author	González, Claudia Beatriz Cantore de Ezcurra, María Leonor
author_facet	González, Claudia Beatriz Cantore de Ezcurra, María Leonor
author_sort	González, Claudia Beatriz
title	Steroidogenesis in immature chicken ovary. Hormonal stimulation of adenylyl cyclase system by luteinizing hormone and β-adrenergic agonists
title_short	Steroidogenesis in immature chicken ovary. Hormonal stimulation of adenylyl cyclase system by luteinizing hormone and β-adrenergic agonists
title_full	Steroidogenesis in immature chicken ovary. Hormonal stimulation of adenylyl cyclase system by luteinizing hormone and β-adrenergic agonists
title_fullStr	Steroidogenesis in immature chicken ovary. Hormonal stimulation of adenylyl cyclase system by luteinizing hormone and β-adrenergic agonists
title_full_unstemmed	Steroidogenesis in immature chicken ovary. Hormonal stimulation of adenylyl cyclase system by luteinizing hormone and β-adrenergic agonists
title_sort	steroidogenesis in immature chicken ovary. hormonal stimulation of adenylyl cyclase system by luteinizing hormone and β-adrenergic agonists
publishDate	1994
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_10656995_v18_n2_p103_Gonzalez http://hdl.handle.net/20.500.12110/paper_10656995_v18_n2_p103_Gonzalez
work_keys_str_mv	AT gonzalezclaudiabeatriz steroidogenesisinimmaturechickenovaryhormonalstimulationofadenylylcyclasesystembyluteinizinghormoneandbadrenergicagonists AT cantoredeezcurramarialeonor steroidogenesisinimmaturechickenovaryhormonalstimulationofadenylylcyclasesystembyluteinizinghormoneandbadrenergicagonists
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Steroidogenesis in immature chicken ovary. Hormonal stimulation of adenylyl cyclase system by luteinizing hormone and β-adrenergic agonists

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