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spelling paper:paper_1557170X_v_n_p4986_Craiem2023-06-08T16:23:16Z Effects of aging on thoracic aorta size and shape: a non-contrast CT study. adult aged aging aortography article audiovisual equipment biological model computer assisted diagnosis computer assisted tomography computer simulation human male methodology middle aged organ size physiology radiography reproducibility sensitivity and specificity thoracic aorta Adult Aged Aging Aorta, Thoracic Aortography Computer Simulation Humans Male Middle Aged Models, Anatomic Models, Cardiovascular Organ Size Radiographic Image Interpretation, Computer-Assisted Reproducibility of Results Sensitivity and Specificity Tomography, X-Ray Computed Measures of atherosclerosis burden like coronary artery calcification are performed using non-contrast heart CT. However, additional information can be derived from these studies, looking beyond the coronary arteries without exposing the patients to further radiation. We present a semi-automated method to assess ascending, arch and descending aorta geometry from non-contrast CT datasets in 250 normotensive patients. We investigated the effect of aging on thoracic aorta morphometry. The algorithm identifies the aortic centerline coordinates following a toroidal path for the curvilinear portion and axial planes for descending aorta. Then it reconstructs oblique planes orthogonal to the centerline direction and a circle fitting process estimates the vessel cross-section. Finally, global thoracic aorta dimensions (diameter, volume and length) and shape (vessel curvature and tortuosity, aortic arch width and height) are calculated. From a multivariate analysis, adjusted for gender and body-size area, aortic volume and arch width were the descriptors that better represented the aortic size and shape alterations with aging. The thoracic aorta suffers an expanding and unfolding process with aging that deserves further attention to prevent aortic aneurisms. 2012 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_1557170X_v_n_p4986_Craiem http://hdl.handle.net/20.500.12110/paper_1557170X_v_n_p4986_Craiem
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic adult
aged
aging
aortography
article
audiovisual equipment
biological model
computer assisted diagnosis
computer assisted tomography
computer simulation
human
male
methodology
middle aged
organ size
physiology
radiography
reproducibility
sensitivity and specificity
thoracic aorta
Adult
Aged
Aging
Aorta, Thoracic
Aortography
Computer Simulation
Humans
Male
Middle Aged
Models, Anatomic
Models, Cardiovascular
Organ Size
Radiographic Image Interpretation, Computer-Assisted
Reproducibility of Results
Sensitivity and Specificity
Tomography, X-Ray Computed
spellingShingle adult
aged
aging
aortography
article
audiovisual equipment
biological model
computer assisted diagnosis
computer assisted tomography
computer simulation
human
male
methodology
middle aged
organ size
physiology
radiography
reproducibility
sensitivity and specificity
thoracic aorta
Adult
Aged
Aging
Aorta, Thoracic
Aortography
Computer Simulation
Humans
Male
Middle Aged
Models, Anatomic
Models, Cardiovascular
Organ Size
Radiographic Image Interpretation, Computer-Assisted
Reproducibility of Results
Sensitivity and Specificity
Tomography, X-Ray Computed
Effects of aging on thoracic aorta size and shape: a non-contrast CT study.
topic_facet adult
aged
aging
aortography
article
audiovisual equipment
biological model
computer assisted diagnosis
computer assisted tomography
computer simulation
human
male
methodology
middle aged
organ size
physiology
radiography
reproducibility
sensitivity and specificity
thoracic aorta
Adult
Aged
Aging
Aorta, Thoracic
Aortography
Computer Simulation
Humans
Male
Middle Aged
Models, Anatomic
Models, Cardiovascular
Organ Size
Radiographic Image Interpretation, Computer-Assisted
Reproducibility of Results
Sensitivity and Specificity
Tomography, X-Ray Computed
description Measures of atherosclerosis burden like coronary artery calcification are performed using non-contrast heart CT. However, additional information can be derived from these studies, looking beyond the coronary arteries without exposing the patients to further radiation. We present a semi-automated method to assess ascending, arch and descending aorta geometry from non-contrast CT datasets in 250 normotensive patients. We investigated the effect of aging on thoracic aorta morphometry. The algorithm identifies the aortic centerline coordinates following a toroidal path for the curvilinear portion and axial planes for descending aorta. Then it reconstructs oblique planes orthogonal to the centerline direction and a circle fitting process estimates the vessel cross-section. Finally, global thoracic aorta dimensions (diameter, volume and length) and shape (vessel curvature and tortuosity, aortic arch width and height) are calculated. From a multivariate analysis, adjusted for gender and body-size area, aortic volume and arch width were the descriptors that better represented the aortic size and shape alterations with aging. The thoracic aorta suffers an expanding and unfolding process with aging that deserves further attention to prevent aortic aneurisms.
title Effects of aging on thoracic aorta size and shape: a non-contrast CT study.
title_short Effects of aging on thoracic aorta size and shape: a non-contrast CT study.
title_full Effects of aging on thoracic aorta size and shape: a non-contrast CT study.
title_fullStr Effects of aging on thoracic aorta size and shape: a non-contrast CT study.
title_full_unstemmed Effects of aging on thoracic aorta size and shape: a non-contrast CT study.
title_sort effects of aging on thoracic aorta size and shape: a non-contrast ct study.
publishDate 2012
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_1557170X_v_n_p4986_Craiem
http://hdl.handle.net/20.500.12110/paper_1557170X_v_n_p4986_Craiem
_version_ 1768545710227062784