Integrating the universe of effector and regulatory immune cell subsets: An emerging role of protein-glycan interactions

The immune system has evolved as a highly effective and dynamic cellular network to signal the presence of invading pathogens and growing tumors and initiate a response that is specific for the danger signal; yet maintaining tolerance to self. In the recent years, data from genomics, proteomics and...

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Detalles Bibliográficos
Autor principal:	Croci Russo, Diego Omar
Publicado:	2010
Materias:	Dendritic cells Galectins Glycoimmunology T helper cells cytokine galectin glycan growth factor article dendritic cell effector cell immunological tolerance immunomodulation immunoregulation inflammation nonhuman priority journal protein protein interaction regulatory T lymphocyte
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_15733955_v6_n4_p348_Pesoa http://hdl.handle.net/20.500.12110/paper_15733955_v6_n4_p348_Pesoa
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_15733955_v6_n4_p348_Pesoa
record_format	dspace
spelling	paper:paper_15733955_v6_n4_p348_Pesoa2025-07-30T19:00:28Z Integrating the universe of effector and regulatory immune cell subsets: An emerging role of protein-glycan interactions Croci Russo, Diego Omar Dendritic cells Galectins Glycoimmunology T helper cells cytokine galectin glycan growth factor article dendritic cell effector cell immunological tolerance immunomodulation immunoregulation inflammation nonhuman priority journal protein protein interaction regulatory T lymphocyte The immune system has evolved as a highly effective and dynamic cellular network to signal the presence of invading pathogens and growing tumors and initiate a response that is specific for the danger signal; yet maintaining tolerance to self. In the recent years, data from genomics, proteomics and glycomics together with classical genetic approaches (knockout and transgenic experiments) and in vivo imaging technologies revealed a complexity of immune cells and molecules which is higher than anticipated. The diversity of effector and regulatory immune cells is entering a new era, in which their specialization might contribute to the development of novel therapeutic approaches in immunopathology. In this context, recent evidence has shed light to an emerging role of protein-glycan interactions in the regulation of immune cell biology. In this review we will integrate traditional and novel subsets of immune cells and will highlight the relevance of protein-glycan systems in modulating their physiology. © 2010 Bentham Science Publishers Ltd. Fil:Croci, D.O. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2010 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_15733955_v6_n4_p348_Pesoa http://hdl.handle.net/20.500.12110/paper_15733955_v6_n4_p348_Pesoa
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Dendritic cells Galectins Glycoimmunology T helper cells cytokine galectin glycan growth factor article dendritic cell effector cell immunological tolerance immunomodulation immunoregulation inflammation nonhuman priority journal protein protein interaction regulatory T lymphocyte
spellingShingle	Dendritic cells Galectins Glycoimmunology T helper cells cytokine galectin glycan growth factor article dendritic cell effector cell immunological tolerance immunomodulation immunoregulation inflammation nonhuman priority journal protein protein interaction regulatory T lymphocyte Croci Russo, Diego Omar Integrating the universe of effector and regulatory immune cell subsets: An emerging role of protein-glycan interactions
topic_facet	Dendritic cells Galectins Glycoimmunology T helper cells cytokine galectin glycan growth factor article dendritic cell effector cell immunological tolerance immunomodulation immunoregulation inflammation nonhuman priority journal protein protein interaction regulatory T lymphocyte
description	The immune system has evolved as a highly effective and dynamic cellular network to signal the presence of invading pathogens and growing tumors and initiate a response that is specific for the danger signal; yet maintaining tolerance to self. In the recent years, data from genomics, proteomics and glycomics together with classical genetic approaches (knockout and transgenic experiments) and in vivo imaging technologies revealed a complexity of immune cells and molecules which is higher than anticipated. The diversity of effector and regulatory immune cells is entering a new era, in which their specialization might contribute to the development of novel therapeutic approaches in immunopathology. In this context, recent evidence has shed light to an emerging role of protein-glycan interactions in the regulation of immune cell biology. In this review we will integrate traditional and novel subsets of immune cells and will highlight the relevance of protein-glycan systems in modulating their physiology. © 2010 Bentham Science Publishers Ltd.
author	Croci Russo, Diego Omar
author_facet	Croci Russo, Diego Omar
author_sort	Croci Russo, Diego Omar
title	Integrating the universe of effector and regulatory immune cell subsets: An emerging role of protein-glycan interactions
title_short	Integrating the universe of effector and regulatory immune cell subsets: An emerging role of protein-glycan interactions
title_full	Integrating the universe of effector and regulatory immune cell subsets: An emerging role of protein-glycan interactions
title_fullStr	Integrating the universe of effector and regulatory immune cell subsets: An emerging role of protein-glycan interactions
title_full_unstemmed	Integrating the universe of effector and regulatory immune cell subsets: An emerging role of protein-glycan interactions
title_sort	integrating the universe of effector and regulatory immune cell subsets: an emerging role of protein-glycan interactions
publishDate	2010
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_15733955_v6_n4_p348_Pesoa http://hdl.handle.net/20.500.12110/paper_15733955_v6_n4_p348_Pesoa
work_keys_str_mv	AT crocirussodiegoomar integratingtheuniverseofeffectorandregulatoryimmunecellsubsetsanemergingroleofproteinglycaninteractions
_version_	1840324071610384384

Integrating the universe of effector and regulatory immune cell subsets: An emerging role of protein-glycan interactions

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