Controversial role of inhibin α-subunit gene in the aetiology of premature ovarian failure

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Background: Premature ovarian failure (POF) is characterized by hypergonadotropic amenorrhoea before the age of 40. Inhibin α-subunit (INHα) gene is proposed as a candidate gene due to its role in negative feedback control of FSH. Methods: Polymorphism -16 C>T of INHα gene was studied in 61 POF p...

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Detalles Bibliográficos
Autores principales: Sundblad, V., Chiauzzi, V.A., Andreone, L., Campo, S., Charreau, E.H., Dain, L.
Formato: Artículo publishedVersion
Lenguaje:Inglés
Publicado: 2006
Materias:
Inhibin levels
Inhibin α-subunit gene
Premature ovarian failure
cytosine
follitropin
inhibin
inhibin A
inhibin B
thymine
adult
allele
alpha chain
amenorrhea
article
confidence interval
controlled study
DNA polymorphism
female
follicular phase
genotype
heterozygosity
human
major clinical study
negative feedback
nucleic acid base substitution
premature ovarian failure
risk assessment
statistical analysis
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_02681161_v21_n5_p1154_Sundblad
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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