Prostaglandin E release by rat medial basal hypothalamus in vitro. Inhibition by melatonin at submicromolar concentrations

Melatonin depressed PGE release by rat medial basal hypothalamus (MBH) in vitro at concentrations 10−8 M or greater. The two-fold increase in PGE release induced by adding 10−4 M norepinephrine to MBH explants was also impaired by melatonin at micromolar or greater concentrations. These data support...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Cardinali, D.P., Ritta, M.N., Fuentes, A.M., Gimeno, M.F., Gimeno, A.L.
Formato:	JOUR
Materias:	Medial basal hypothalamus Melatonin Prostaglandins melatonin prostaglandin E animal article drug effect hypothalamus in vitro study male metabolism rat Animals Hypothalamus Hypothalamus, Middle Male Prostaglandins E Rats
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00142999_v67_n1_p151_Cardinali
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	todo:paper_00142999_v67_n1_p151_Cardinali
record_format	dspace
spelling	todo:paper_00142999_v67_n1_p151_Cardinali2023-10-03T14:12:09Z Prostaglandin E release by rat medial basal hypothalamus in vitro. Inhibition by melatonin at submicromolar concentrations Cardinali, D.P. Ritta, M.N. Fuentes, A.M. Gimeno, M.F. Gimeno, A.L. Medial basal hypothalamus Melatonin Prostaglandins melatonin prostaglandin E animal article drug effect hypothalamus in vitro study male metabolism rat Animals Hypothalamus Hypothalamus, Middle Male Melatonin Prostaglandins E Rats Melatonin depressed PGE release by rat medial basal hypothalamus (MBH) in vitro at concentrations 10−8 M or greater. The two-fold increase in PGE release induced by adding 10−4 M norepinephrine to MBH explants was also impaired by melatonin at micromolar or greater concentrations. These data support the view that melatonin is a physiological inhibitor of PG synthesis in MBH. © 1980, All rights reserved. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00142999_v67_n1_p151_Cardinali
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	Medial basal hypothalamus Melatonin Prostaglandins melatonin prostaglandin E animal article drug effect hypothalamus in vitro study male metabolism rat Animals Hypothalamus Hypothalamus, Middle Male Melatonin Prostaglandins E Rats
spellingShingle	Medial basal hypothalamus Melatonin Prostaglandins melatonin prostaglandin E animal article drug effect hypothalamus in vitro study male metabolism rat Animals Hypothalamus Hypothalamus, Middle Male Melatonin Prostaglandins E Rats Cardinali, D.P. Ritta, M.N. Fuentes, A.M. Gimeno, M.F. Gimeno, A.L. Prostaglandin E release by rat medial basal hypothalamus in vitro. Inhibition by melatonin at submicromolar concentrations
topic_facet	Medial basal hypothalamus Melatonin Prostaglandins melatonin prostaglandin E animal article drug effect hypothalamus in vitro study male metabolism rat Animals Hypothalamus Hypothalamus, Middle Male Melatonin Prostaglandins E Rats
description	Melatonin depressed PGE release by rat medial basal hypothalamus (MBH) in vitro at concentrations 10−8 M or greater. The two-fold increase in PGE release induced by adding 10−4 M norepinephrine to MBH explants was also impaired by melatonin at micromolar or greater concentrations. These data support the view that melatonin is a physiological inhibitor of PG synthesis in MBH. © 1980, All rights reserved.
format	JOUR
author	Cardinali, D.P. Ritta, M.N. Fuentes, A.M. Gimeno, M.F. Gimeno, A.L.
author_facet	Cardinali, D.P. Ritta, M.N. Fuentes, A.M. Gimeno, M.F. Gimeno, A.L.
author_sort	Cardinali, D.P.
title	Prostaglandin E release by rat medial basal hypothalamus in vitro. Inhibition by melatonin at submicromolar concentrations
title_short	Prostaglandin E release by rat medial basal hypothalamus in vitro. Inhibition by melatonin at submicromolar concentrations
title_full	Prostaglandin E release by rat medial basal hypothalamus in vitro. Inhibition by melatonin at submicromolar concentrations
title_fullStr	Prostaglandin E release by rat medial basal hypothalamus in vitro. Inhibition by melatonin at submicromolar concentrations
title_full_unstemmed	Prostaglandin E release by rat medial basal hypothalamus in vitro. Inhibition by melatonin at submicromolar concentrations
title_sort	prostaglandin e release by rat medial basal hypothalamus in vitro. inhibition by melatonin at submicromolar concentrations
url	http://hdl.handle.net/20.500.12110/paper_00142999_v67_n1_p151_Cardinali
work_keys_str_mv	AT cardinalidp prostaglandinereleasebyratmedialbasalhypothalamusinvitroinhibitionbymelatoninatsubmicromolarconcentrations AT rittamn prostaglandinereleasebyratmedialbasalhypothalamusinvitroinhibitionbymelatoninatsubmicromolarconcentrations AT fuentesam prostaglandinereleasebyratmedialbasalhypothalamusinvitroinhibitionbymelatoninatsubmicromolarconcentrations AT gimenomf prostaglandinereleasebyratmedialbasalhypothalamusinvitroinhibitionbymelatoninatsubmicromolarconcentrations AT gimenoal prostaglandinereleasebyratmedialbasalhypothalamusinvitroinhibitionbymelatoninatsubmicromolarconcentrations
_version_	1807317253803212800

Prostaglandin E release by rat medial basal hypothalamus in vitro. Inhibition by melatonin at submicromolar concentrations

Ejemplares similares