Effect of naloxone on the nocturnal rise of rat pineal melatonin content
Rats exposed to 14 light: 10 h dark photoperiods were given naloxone hydrochloride (10 mg/kg) s.c. 2 h before and 5 h after the lights were turned off. A smaller noctúrnal pineal melatonin peak, as well as a slower decrease from peak values were observed in naloxone-treated rats. Naloxone (up to 10-...
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| Formato: | JOUR |
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_00142999_v98_n2_p261_Lowenstein |
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todo:paper_00142999_v98_n2_p261_Lowenstein2023-10-03T14:12:12Z Effect of naloxone on the nocturnal rise of rat pineal melatonin content Lowenstein, P.R. Pereyra, E.N. Solveyra, C.G. Cardinali, D.P. Endogenous opioids Melatonin Naloxone Norepinephrine Pineal gland endorphin melatonin naloxone neurotransmitter noradrenalin radioisotope animal experiment central nervous system endocrine system nervous system nonhuman noradrenalin h 3 photoperiodicity pineal body rat subcutaneous drug administration synapse Animal Male Melatonin Naloxone Pineal Gland Rats Rats, Inbred Strains Support, Non-U.S. Gov't Rats exposed to 14 light: 10 h dark photoperiods were given naloxone hydrochloride (10 mg/kg) s.c. 2 h before and 5 h after the lights were turned off. A smaller noctúrnal pineal melatonin peak, as well as a slower decrease from peak values were observed in naloxone-treated rats. Naloxone (up to 10-4M) did not affect either in vitro rat pineal melatonin content or 3H-labeled transmitter release in glands previously incubated with [3H]norepinephrine. Hence a central, rather than a peripheral opioid synapse appears to be involved in naloxone effect on nocturnal melatonin increase. © 1984. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00142999_v98_n2_p261_Lowenstein |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Endogenous opioids Melatonin Naloxone Norepinephrine Pineal gland endorphin melatonin naloxone neurotransmitter noradrenalin radioisotope animal experiment central nervous system endocrine system nervous system nonhuman noradrenalin h 3 photoperiodicity pineal body rat subcutaneous drug administration synapse Animal Male Melatonin Naloxone Pineal Gland Rats Rats, Inbred Strains Support, Non-U.S. Gov't |
| spellingShingle |
Endogenous opioids Melatonin Naloxone Norepinephrine Pineal gland endorphin melatonin naloxone neurotransmitter noradrenalin radioisotope animal experiment central nervous system endocrine system nervous system nonhuman noradrenalin h 3 photoperiodicity pineal body rat subcutaneous drug administration synapse Animal Male Melatonin Naloxone Pineal Gland Rats Rats, Inbred Strains Support, Non-U.S. Gov't Lowenstein, P.R. Pereyra, E.N. Solveyra, C.G. Cardinali, D.P. Effect of naloxone on the nocturnal rise of rat pineal melatonin content |
| topic_facet |
Endogenous opioids Melatonin Naloxone Norepinephrine Pineal gland endorphin melatonin naloxone neurotransmitter noradrenalin radioisotope animal experiment central nervous system endocrine system nervous system nonhuman noradrenalin h 3 photoperiodicity pineal body rat subcutaneous drug administration synapse Animal Male Melatonin Naloxone Pineal Gland Rats Rats, Inbred Strains Support, Non-U.S. Gov't |
| description |
Rats exposed to 14 light: 10 h dark photoperiods were given naloxone hydrochloride (10 mg/kg) s.c. 2 h before and 5 h after the lights were turned off. A smaller noctúrnal pineal melatonin peak, as well as a slower decrease from peak values were observed in naloxone-treated rats. Naloxone (up to 10-4M) did not affect either in vitro rat pineal melatonin content or 3H-labeled transmitter release in glands previously incubated with [3H]norepinephrine. Hence a central, rather than a peripheral opioid synapse appears to be involved in naloxone effect on nocturnal melatonin increase. © 1984. |
| format |
JOUR |
| author |
Lowenstein, P.R. Pereyra, E.N. Solveyra, C.G. Cardinali, D.P. |
| author_facet |
Lowenstein, P.R. Pereyra, E.N. Solveyra, C.G. Cardinali, D.P. |
| author_sort |
Lowenstein, P.R. |
| title |
Effect of naloxone on the nocturnal rise of rat pineal melatonin content |
| title_short |
Effect of naloxone on the nocturnal rise of rat pineal melatonin content |
| title_full |
Effect of naloxone on the nocturnal rise of rat pineal melatonin content |
| title_fullStr |
Effect of naloxone on the nocturnal rise of rat pineal melatonin content |
| title_full_unstemmed |
Effect of naloxone on the nocturnal rise of rat pineal melatonin content |
| title_sort |
effect of naloxone on the nocturnal rise of rat pineal melatonin content |
| url |
http://hdl.handle.net/20.500.12110/paper_00142999_v98_n2_p261_Lowenstein |
| work_keys_str_mv |
AT lowensteinpr effectofnaloxoneonthenocturnalriseofratpinealmelatonincontent AT pereyraen effectofnaloxoneonthenocturnalriseofratpinealmelatonincontent AT solveyracg effectofnaloxoneonthenocturnalriseofratpinealmelatonincontent AT cardinalidp effectofnaloxoneonthenocturnalriseofratpinealmelatonincontent |
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