Fibronectin rescues estrogen receptor α from lysosomal degradation in breast cancer cells

Estrogen receptor α (ERα) is expressed in tissues as diverse as brains and mammary glands. In breast cancer, ERα is a key regulator of tumor progression. Therefore, understanding what activates ERα is critical for cancer treatment in particular and cell biology in general. Using biochemical approach...

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Detalles Bibliográficos
Autores principales:	Sampayo, R.G., Toscani, A.M., Rubashkin, M.G., Thi, K., Masullo, L.A., Violi, I.L., Lakins, J.N., Cáceres, A., Hines, W.C., Leskow, F.C., Stefani, F.D., Chialvo, D.R., Bissell, M.J., Weaver, V.M., Simian, M.
Formato:	JOUR
Materias:	beta1 integrin estrogen estrogen receptor alpha fibronectin Article biochemical analysis breast cancer breast tissue cancer cell cell compartmentalization cell fate cell vacuole controlled study endocytosis endosome estrogen activity extracellular matrix human human cell human tissue intracellular transport lysosome microscopy priority journal protein degradation protein function protein localization protein protein interaction signal transduction
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00219525_v217_n8_p2777_Sampayo
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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