Differential effect of αdifluoromethyl‐ornithine on the proliferation of balb 3T3 and chemically transformed 3T3 cells

In order to study the effect of polyamine depletion on growth and proliferation of untransformed and chemically transformed cells, α‐difluoromethyl‐ornithine (DFMO) was added to cultures of 3T3 cells and their benzo[a]pyrene derivative BP‐3T3. Both types of cells stopped their proliferation after 72...

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Detalles Bibliográficos
Autores principales: Medrano, E.E., Goldemberg, S.H., Algranati, I.D.
Formato: JOUR
Materias:
benzo[a]pyrene
eflornithine
polyamine
putrescine
radioisotope
spermidine
animal cell
cancer chemotherapy
cell culture
cell proliferation
cell transformation
drug therapy
in vitro study
mouse
nonhuman
reticuloendothelial system
therapy
thymidine h 3
Animal
Benzo(a)pyrene
Benzopyrenes
Carcinogens
Cell Division
Cell Transformation, Neoplastic
Cells, Cultured
DNA Replication
Eflornithine
Interphase
Kinetics
Mice
Mice, Inbred BALB C
Ornithine
Ornithine Decarboxylase
Putrescine
Support, Non-U.S. Gov't
Transcription, Genetic
Translation, Genetic
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00219541_v117_n2_p141_Medrano
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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