Regulation of the glucocorticoid response to stress-related disorders by the Hsp90-binding immunophilin FKBP51

Immunophilin is the collective name given to a family of proteins that bind immunosuppressive drugs: Some immunophilins are Hsp90-binding cochaperones that affect steroid receptor function. Mood and anxiety disorders are stress-related diseases characterized by an impaired function of the mineraloco...

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Detalles Bibliográficos
Autores principales: Galigniana, N.M., Ballmer, L.T., Toneatto, J., Erlejman, A.G., Lagadari, M., Galigniana, M.D.
Formato: JOUR
Materias:
depression
glucocorticoid receptor
Hsp90
Hypothalamic- Pituitary-Adrenal axis
immunophilin
tetratricopeptide repeat domain
chaperone
fk 506 binding protein
fk 506 binding protein 51
glucocorticoid
heat shock protein 90
mineralocorticoid receptor
peptidylprolyl isomerase
steroid receptor
unclassified drug
anxiety disorder
Cushing disease
disease association
disease course
drug resistance
genetic association
genetic variability
hormone response
human
Human immunodeficiency virus infection
hypothalamus hypophysis adrenal system
immune response
mental stress
mood disorder
nonhuman
posttraumatic stress disorder
priority journal
protein binding
protein defect
protein domain
protein expression
protein function
protein polymorphism
protein structure
protein targeting
regulatory mechanism
review
risk factor
signal transduction
stress
Animals
Anxiety Disorders
Glucocorticoids
Humans
Mood Disorders
Peptidylprolyl Isomerase
Receptors, Steroid
Stress Disorders, Post-Traumatic
Tacrolimus Binding Proteins
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00223042_v122_n1_p4_Galigniana
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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