Chagasic IgG modifies the activity of sarcolemmal ATPases through a β adrenergic mechanism

The effect of anti β adrenoceptor IgG from chagasic sera upon Ca2+-ATPase and Na++K+-ATPase of myocardial membrane was studied. Chagasic IgG stimulated Ca2+-ATPase and inhibited Na++K+-ATPase activities. Both enzymatic effects of the IgG could be prevented after β adrenoceptor blockade or after the...

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Detalles Bibliográficos
Autores principales: Pascual, J., Borda, E., Sterin-Borda, L.
Formato: JOUR
Materias:
adenosine triphosphatase (calcium magnesium)
adenosine triphosphatase (calcium)
adenosine triphosphatase (potassium sodium)
Adrenergic beta Agonists
beta adrenergic receptor
beta adrenergic receptor stimulating agent
Ca(2+) Mg(2+) ATPase
Ca(2+) Transporting ATPase
immunoglobulin G
isoprenaline
Na(+) K(+) Exchanging ATPase
propranolol
adult
animal
article
Chagas disease
enzymology
erythrocyte
guinea pig
human
immunology
male
metabolism
physiology
sarcolemma
turkey (bird)
Adrenergic beta-Agonists
Adult
Animal
Ca(2+) Mg(2+)-ATPase
Ca(2+)-Transporting ATPase
Chagas Disease
Erythrocytes
Guinea Pigs
Human
Immunoglobulin G
Isoproterenol
Male
Na(+)-K(+)-Exchanging ATPase
Propranolol
Receptors, Adrenergic, beta
Sarcolemma
Support, Non-U.S. Gov't
Turkeys
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00243205_v40_n4_p313_Pascual
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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