Partial starvation, and "in vitro" contractions of rat uterine smooth muscle. Levels of glygogen and trigly-cerides

The effects of a restricted-diet (50% of the normal intake during 25 days) on the isometric developed tension (IDT) of uterine horns isolated from diestrous non-cycling rats, were explored. After 60 minutes following isolation and mounting the IDT of controls suspended in glucose containing solution...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Sterin, A.B.F., Linares, J.A., Goldrsij, A., Gimeno, M.F., Gimeno, A.L.
Formato: JOUR
Materias:
rat
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00316989_v15_n2_p145_Sterin
Aporte de:
id todo:paper_00316989_v15_n2_p145_Sterin
record_format dspace
spelling todo:paper_00316989_v15_n2_p145_Sterin2023-10-03T14:41:27Z Partial starvation, and "in vitro" contractions of rat uterine smooth muscle. Levels of glygogen and trigly-cerides Sterin, A.B.F. Linares, J.A. Goldrsij, A. Gimeno, M.F. Gimeno, A.L. 3 methylglucose glycogen oxidopamine propranolol sotalol triacylglycerol animal cell drug efficacy female genital system muscle myometrium nonhuman rat smooth muscle starvation uterus contraction 3-O-Methylglucose Animals Female Glycogen Hydroxydopamines Methylglucosides Oxidopamine Propranolol Rats Rats, Inbred Strains Starvation Triglycerides Uterine Contraction Uterus The effects of a restricted-diet (50% of the normal intake during 25 days) on the isometric developed tension (IDT) of uterine horns isolated from diestrous non-cycling rats, were explored. After 60 minutes following isolation and mounting the IDT of controls suspended in glucose containing solution was higher than in preparations from underfed animals but this was no the case in the absence of glucose. Glycogen levels of controls at 60 minutes were smaller in substrate-free than in the presence of glucose whereas no change was detected in horns from restricted-diet rats. Preparations from underfed animals had a significantly augmented basal concentration of triglycerides which diminished at 60 minutes following the renoval of glucose from the suspending solution. This effect was abolished by the addition of 3-o-methyl glucose and by blockers of beta-adrenoreceptors such as propranolol or MJ-1999. A similar situation occurs when the animals were injected prior killing with 6-hydroxydopamine. © 1983 The Italian Pharmacological Society. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00316989_v15_n2_p145_Sterin
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic 3 methylglucose
glycogen
oxidopamine
propranolol
sotalol
triacylglycerol
animal cell
drug efficacy
female genital system
muscle
myometrium
nonhuman
rat
smooth muscle
starvation
uterus contraction
3-O-Methylglucose
Animals
Female
Glycogen
Hydroxydopamines
Methylglucosides
Oxidopamine
Propranolol
Rats
Rats, Inbred Strains
Starvation
Triglycerides
Uterine Contraction
Uterus
spellingShingle 3 methylglucose
glycogen
oxidopamine
propranolol
sotalol
triacylglycerol
animal cell
drug efficacy
female genital system
muscle
myometrium
nonhuman
rat
smooth muscle
starvation
uterus contraction
3-O-Methylglucose
Animals
Female
Glycogen
Hydroxydopamines
Methylglucosides
Oxidopamine
Propranolol
Rats
Rats, Inbred Strains
Starvation
Triglycerides
Uterine Contraction
Uterus
Sterin, A.B.F.
Linares, J.A.
Goldrsij, A.
Gimeno, M.F.
Gimeno, A.L.
Partial starvation, and "in vitro" contractions of rat uterine smooth muscle. Levels of glygogen and trigly-cerides
topic_facet 3 methylglucose
glycogen
oxidopamine
propranolol
sotalol
triacylglycerol
animal cell
drug efficacy
female genital system
muscle
myometrium
nonhuman
rat
smooth muscle
starvation
uterus contraction
3-O-Methylglucose
Animals
Female
Glycogen
Hydroxydopamines
Methylglucosides
Oxidopamine
Propranolol
Rats
Rats, Inbred Strains
Starvation
Triglycerides
Uterine Contraction
Uterus
description The effects of a restricted-diet (50% of the normal intake during 25 days) on the isometric developed tension (IDT) of uterine horns isolated from diestrous non-cycling rats, were explored. After 60 minutes following isolation and mounting the IDT of controls suspended in glucose containing solution was higher than in preparations from underfed animals but this was no the case in the absence of glucose. Glycogen levels of controls at 60 minutes were smaller in substrate-free than in the presence of glucose whereas no change was detected in horns from restricted-diet rats. Preparations from underfed animals had a significantly augmented basal concentration of triglycerides which diminished at 60 minutes following the renoval of glucose from the suspending solution. This effect was abolished by the addition of 3-o-methyl glucose and by blockers of beta-adrenoreceptors such as propranolol or MJ-1999. A similar situation occurs when the animals were injected prior killing with 6-hydroxydopamine. © 1983 The Italian Pharmacological Society.
format JOUR
author Sterin, A.B.F.
Linares, J.A.
Goldrsij, A.
Gimeno, M.F.
Gimeno, A.L.
author_facet Sterin, A.B.F.
Linares, J.A.
Goldrsij, A.
Gimeno, M.F.
Gimeno, A.L.
author_sort Sterin, A.B.F.
title Partial starvation, and "in vitro" contractions of rat uterine smooth muscle. Levels of glygogen and trigly-cerides
title_short Partial starvation, and "in vitro" contractions of rat uterine smooth muscle. Levels of glygogen and trigly-cerides
title_full Partial starvation, and "in vitro" contractions of rat uterine smooth muscle. Levels of glygogen and trigly-cerides
title_fullStr Partial starvation, and "in vitro" contractions of rat uterine smooth muscle. Levels of glygogen and trigly-cerides
title_full_unstemmed Partial starvation, and "in vitro" contractions of rat uterine smooth muscle. Levels of glygogen and trigly-cerides
title_sort partial starvation, and "in vitro" contractions of rat uterine smooth muscle. levels of glygogen and trigly-cerides
url http://hdl.handle.net/20.500.12110/paper_00316989_v15_n2_p145_Sterin
work_keys_str_mv AT sterinabf partialstarvationandinvitrocontractionsofratuterinesmoothmusclelevelsofglygogenandtriglycerides
AT linaresja partialstarvationandinvitrocontractionsofratuterinesmoothmusclelevelsofglygogenandtriglycerides
AT goldrsija partialstarvationandinvitrocontractionsofratuterinesmoothmusclelevelsofglygogenandtriglycerides
AT gimenomf partialstarvationandinvitrocontractionsofratuterinesmoothmusclelevelsofglygogenandtriglycerides
AT gimenoal partialstarvationandinvitrocontractionsofratuterinesmoothmusclelevelsofglygogenandtriglycerides
_version_ 1807321976842223616