Patagonicoside A: A novel antifungal disulfated triterpene glycoside from the sea cucumber Psolus patagonicus
A new triterpene glycoside, patagonicoside A (1), has been isolated from the sea cucumber Psolus patagonicus and its structure has been elucidated by 1D and 2D NMR (1H-, 13C-, 1H-1H COSY, HETCOR, COLOC and NOESY spectra), FAB-MS and chemical evidence. Compound 1 is a disulfated tetrasaccharide with...
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| Formato: | JOUR |
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_00404020_v57_n47_p9563_Murray |
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todo:paper_00404020_v57_n47_p9563_Murray2023-10-03T14:50:40Z Patagonicoside A: A novel antifungal disulfated triterpene glycoside from the sea cucumber Psolus patagonicus Murray, A.P. Muniaín, C. Seldes, A.M. Maier, M.S. Antifungal activity Glycosides Holothuroidea Psolus patagonicus Triterpenes antifungal agent glycoside patagonicoside a triterpenic glycoside unclassified drug antifungal activity article carbon nuclear magnetic resonance Cladosporium cucumerinum controlled study desulfurization dose response drug isolation drug structure echinoderm mass spectrometry nonhuman priority journal proton nuclear magnetic resonance A new triterpene glycoside, patagonicoside A (1), has been isolated from the sea cucumber Psolus patagonicus and its structure has been elucidated by 1D and 2D NMR (1H-, 13C-, 1H-1H COSY, HETCOR, COLOC and NOESY spectra), FAB-MS and chemical evidence. Compound 1 is a disulfated tetrasaccharide with a new aglycon moiety. Patagonicoside A (1) exhibits considerable antifungal activity against the pathogenic fungus Cladosporium cucumerinum. © 2001 Elsevier Science Ltd. All rights reserved. Fil:Seldes, A.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Maier, M.S. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00404020_v57_n47_p9563_Murray |
| institution |
Universidad de Buenos Aires |
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I-28 |
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R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Antifungal activity Glycosides Holothuroidea Psolus patagonicus Triterpenes antifungal agent glycoside patagonicoside a triterpenic glycoside unclassified drug antifungal activity article carbon nuclear magnetic resonance Cladosporium cucumerinum controlled study desulfurization dose response drug isolation drug structure echinoderm mass spectrometry nonhuman priority journal proton nuclear magnetic resonance |
| spellingShingle |
Antifungal activity Glycosides Holothuroidea Psolus patagonicus Triterpenes antifungal agent glycoside patagonicoside a triterpenic glycoside unclassified drug antifungal activity article carbon nuclear magnetic resonance Cladosporium cucumerinum controlled study desulfurization dose response drug isolation drug structure echinoderm mass spectrometry nonhuman priority journal proton nuclear magnetic resonance Murray, A.P. Muniaín, C. Seldes, A.M. Maier, M.S. Patagonicoside A: A novel antifungal disulfated triterpene glycoside from the sea cucumber Psolus patagonicus |
| topic_facet |
Antifungal activity Glycosides Holothuroidea Psolus patagonicus Triterpenes antifungal agent glycoside patagonicoside a triterpenic glycoside unclassified drug antifungal activity article carbon nuclear magnetic resonance Cladosporium cucumerinum controlled study desulfurization dose response drug isolation drug structure echinoderm mass spectrometry nonhuman priority journal proton nuclear magnetic resonance |
| description |
A new triterpene glycoside, patagonicoside A (1), has been isolated from the sea cucumber Psolus patagonicus and its structure has been elucidated by 1D and 2D NMR (1H-, 13C-, 1H-1H COSY, HETCOR, COLOC and NOESY spectra), FAB-MS and chemical evidence. Compound 1 is a disulfated tetrasaccharide with a new aglycon moiety. Patagonicoside A (1) exhibits considerable antifungal activity against the pathogenic fungus Cladosporium cucumerinum. © 2001 Elsevier Science Ltd. All rights reserved. |
| format |
JOUR |
| author |
Murray, A.P. Muniaín, C. Seldes, A.M. Maier, M.S. |
| author_facet |
Murray, A.P. Muniaín, C. Seldes, A.M. Maier, M.S. |
| author_sort |
Murray, A.P. |
| title |
Patagonicoside A: A novel antifungal disulfated triterpene glycoside from the sea cucumber Psolus patagonicus |
| title_short |
Patagonicoside A: A novel antifungal disulfated triterpene glycoside from the sea cucumber Psolus patagonicus |
| title_full |
Patagonicoside A: A novel antifungal disulfated triterpene glycoside from the sea cucumber Psolus patagonicus |
| title_fullStr |
Patagonicoside A: A novel antifungal disulfated triterpene glycoside from the sea cucumber Psolus patagonicus |
| title_full_unstemmed |
Patagonicoside A: A novel antifungal disulfated triterpene glycoside from the sea cucumber Psolus patagonicus |
| title_sort |
patagonicoside a: a novel antifungal disulfated triterpene glycoside from the sea cucumber psolus patagonicus |
| url |
http://hdl.handle.net/20.500.12110/paper_00404020_v57_n47_p9563_Murray |
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