Novel withanolides from jaborosa sativa

Four new withanolides [1—4] have been isolated from the aerial parts of Jaborosa sativa. Jaborosalactones R[1], S[2], and T [3] contain a hemiketal (or ketal) ring formed between a 21-hydroxyl and a 12-ketone and the characteristic δ-lactone side-chain of the withanolides. Jaborosalactone U [4] poss...

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Autores principales: Bonetto, G.M., Gil, R.R., Oberti, J.C., Veleiro, A.S., Burton, G.
Formato: JOUR
Materias:
jaborosalactone r
jaborosalactone s
jaborosalactone t
jaborosalactone u
trechonolide a
unclassified drug
withanolide
Argentina
article
drug conformation
drug isolation
drug structure
medicinal plant
nonhuman
stereochemistry
Jaborosa
Jaborosa sativa
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_01633864_v58_n5_p705_Bonetto
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id todo:paper_01633864_v58_n5_p705_Bonetto
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spelling todo:paper_01633864_v58_n5_p705_Bonetto2023-10-03T15:02:06Z Novel withanolides from jaborosa sativa Bonetto, G.M. Gil, R.R. Oberti, J.C. Veleiro, A.S. Burton, G. jaborosalactone r jaborosalactone s jaborosalactone t jaborosalactone u trechonolide a unclassified drug withanolide Argentina article drug conformation drug isolation drug structure medicinal plant nonhuman stereochemistry Jaborosa Jaborosa sativa Four new withanolides [1—4] have been isolated from the aerial parts of Jaborosa sativa. Jaborosalactones R[1], S[2], and T [3] contain a hemiketal (or ketal) ring formed between a 21-hydroxyl and a 12-ketone and the characteristic δ-lactone side-chain of the withanolides. Jaborosalactone U [4] possesses an epoxy-γ-lactone side-chain and was identified as the 24,25-epoxy analogue of trechonolide A [5]. © 1995, American Chemical Society. All rights reserved. Fil:Veleiro, A.S. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Burton, G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_01633864_v58_n5_p705_Bonetto
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic jaborosalactone r
jaborosalactone s
jaborosalactone t
jaborosalactone u
trechonolide a
unclassified drug
withanolide
Argentina
article
drug conformation
drug isolation
drug structure
medicinal plant
nonhuman
stereochemistry
Jaborosa
Jaborosa sativa
spellingShingle jaborosalactone r
jaborosalactone s
jaborosalactone t
jaborosalactone u
trechonolide a
unclassified drug
withanolide
Argentina
article
drug conformation
drug isolation
drug structure
medicinal plant
nonhuman
stereochemistry
Jaborosa
Jaborosa sativa
Bonetto, G.M.
Gil, R.R.
Oberti, J.C.
Veleiro, A.S.
Burton, G.
Novel withanolides from jaborosa sativa
topic_facet jaborosalactone r
jaborosalactone s
jaborosalactone t
jaborosalactone u
trechonolide a
unclassified drug
withanolide
Argentina
article
drug conformation
drug isolation
drug structure
medicinal plant
nonhuman
stereochemistry
Jaborosa
Jaborosa sativa
description Four new withanolides [1—4] have been isolated from the aerial parts of Jaborosa sativa. Jaborosalactones R[1], S[2], and T [3] contain a hemiketal (or ketal) ring formed between a 21-hydroxyl and a 12-ketone and the characteristic δ-lactone side-chain of the withanolides. Jaborosalactone U [4] possesses an epoxy-γ-lactone side-chain and was identified as the 24,25-epoxy analogue of trechonolide A [5]. © 1995, American Chemical Society. All rights reserved.
format JOUR
author Bonetto, G.M.
Gil, R.R.
Oberti, J.C.
Veleiro, A.S.
Burton, G.
author_facet Bonetto, G.M.
Gil, R.R.
Oberti, J.C.
Veleiro, A.S.
Burton, G.
author_sort Bonetto, G.M.
title Novel withanolides from jaborosa sativa
title_short Novel withanolides from jaborosa sativa
title_full Novel withanolides from jaborosa sativa
title_fullStr Novel withanolides from jaborosa sativa
title_full_unstemmed Novel withanolides from jaborosa sativa
title_sort novel withanolides from jaborosa sativa
url http://hdl.handle.net/20.500.12110/paper_01633864_v58_n5_p705_Bonetto
work_keys_str_mv AT bonettogm novelwithanolidesfromjaborosasativa
AT gilrr novelwithanolidesfromjaborosasativa
AT obertijc novelwithanolidesfromjaborosasativa
AT veleiroas novelwithanolidesfromjaborosasativa
AT burtong novelwithanolidesfromjaborosasativa
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