Developmental changes in calcium channel types mediating central synaptic transmission

Multiple types of high-voltage-activated Ca2+ channels trigger neurotransmitter release at the mammalian central synapse. Among them, the ω-conotoxin GVIA-sensitive N-type channels and the ω-Aga-IVA-sensitive P/Q- type channels mediate fast synaptic transmission. However, at most central synapses, i...

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Detalles Bibliográficos
Autores principales: Iwasaki, S., Momiyama, A., Uchitel, O.D., Takahashi, T.
Formato: JOUR
Materias:
Central synapse
N-type calcium channels
P/Q-type calcium channels
Postnatal development
Slice
Transmitter release
calcium channel
neurotransmitter
omega conotoxin
animal tissue
article
brain cortex
calcium current
controlled study
GABAergic system
nerve ending
neurotransmitter release
nonhuman
postnatal development
priority journal
rat
spinal cord dorsal horn
synapse
synaptic transmission
2-Amino-5-phosphonovalerate
6-Cyano-7-nitroquinoxaline-2,3-dione
Age Factors
Animals
Brain Chemistry
Calcium Channel Blockers
Calcium Channels, N-Type
Calcium Channels, R-Type
Central Nervous System
Evoked Potentials
Excitatory Amino Acid Antagonists
Excitatory Postsynaptic Potentials
gamma-Aminobutyric Acid
Glycine Agents
omega-Agatoxin IVA
omega-Conotoxins
Organ Culture Techniques
Rats
Rats, Wistar
Strychnine
Synaptic Transmission
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_02706474_v20_n1_p59_Iwasaki
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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