Discrimination surfaces with application to region-specific brain asymmetry analysis
Discrimination surfaces are here introduced as a diagnostic tool for localizing brain regions where discrimination between diseased and nondiseased participants is higher. To estimate discrimination surfaces, we introduce a Mann-Whitney type of statistic for random fields and present large-sample re...
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| Formato: | JOUR |
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_02776715_v37_n11_p1859_Martos |
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todo:paper_02776715_v37_n11_p1859_Martos2023-10-03T15:16:13Z Discrimination surfaces with application to region-specific brain asymmetry analysis Martos, G. de Carvalho, M. conditional area under the curve distance to symmetry Mann-Whitney statistic neuroanatomical asymmetry receiver operating characteristic schizophrenia Discrimination surfaces are here introduced as a diagnostic tool for localizing brain regions where discrimination between diseased and nondiseased participants is higher. To estimate discrimination surfaces, we introduce a Mann-Whitney type of statistic for random fields and present large-sample results characterizing its asymptotic behavior. Simulation results demonstrate that our estimator accurately recovers the true surface and corresponding interval of maximal discrimination. The empirical analysis suggests that in the anterior region of the brain, schizophrenic patients tend to present lower local asymmetry scores in comparison with participants in the control group. Copyright © 2018 John Wiley & Sons, Ltd. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_02776715_v37_n11_p1859_Martos |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
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Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
conditional area under the curve distance to symmetry Mann-Whitney statistic neuroanatomical asymmetry receiver operating characteristic schizophrenia |
| spellingShingle |
conditional area under the curve distance to symmetry Mann-Whitney statistic neuroanatomical asymmetry receiver operating characteristic schizophrenia Martos, G. de Carvalho, M. Discrimination surfaces with application to region-specific brain asymmetry analysis |
| topic_facet |
conditional area under the curve distance to symmetry Mann-Whitney statistic neuroanatomical asymmetry receiver operating characteristic schizophrenia |
| description |
Discrimination surfaces are here introduced as a diagnostic tool for localizing brain regions where discrimination between diseased and nondiseased participants is higher. To estimate discrimination surfaces, we introduce a Mann-Whitney type of statistic for random fields and present large-sample results characterizing its asymptotic behavior. Simulation results demonstrate that our estimator accurately recovers the true surface and corresponding interval of maximal discrimination. The empirical analysis suggests that in the anterior region of the brain, schizophrenic patients tend to present lower local asymmetry scores in comparison with participants in the control group. Copyright © 2018 John Wiley & Sons, Ltd. |
| format |
JOUR |
| author |
Martos, G. de Carvalho, M. |
| author_facet |
Martos, G. de Carvalho, M. |
| author_sort |
Martos, G. |
| title |
Discrimination surfaces with application to region-specific brain asymmetry analysis |
| title_short |
Discrimination surfaces with application to region-specific brain asymmetry analysis |
| title_full |
Discrimination surfaces with application to region-specific brain asymmetry analysis |
| title_fullStr |
Discrimination surfaces with application to region-specific brain asymmetry analysis |
| title_full_unstemmed |
Discrimination surfaces with application to region-specific brain asymmetry analysis |
| title_sort |
discrimination surfaces with application to region-specific brain asymmetry analysis |
| url |
http://hdl.handle.net/20.500.12110/paper_02776715_v37_n11_p1859_Martos |
| work_keys_str_mv |
AT martosg discriminationsurfaceswithapplicationtoregionspecificbrainasymmetryanalysis AT decarvalhom discriminationsurfaceswithapplicationtoregionspecificbrainasymmetryanalysis |
| _version_ |
1807317563196047360 |