Administration of a gonadotropin-releasing hormone agonist affects corpus luteum vascular stability and development and induces luteal apoptosis in a rat model of ovarian hyperstimulation syndrome

Ovarian hyperstimulation syndrome (OHSS) is a complication of ovarian stimulation with gonadotropins followed by the administration of human chorionic gonadotropin (hCG) to trigger the final steps of oocyte maturation. Gonadotropin-releasing hormone (GnRH) analogs are thought to be effective in prev...

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Detalles Bibliográficos
Autores principales: Scotti, L., Irusta, G., Abramovich, D., Tesone, M., Parborell, F.
Formato: JOUR
Materias:
Angiogenesis
GnRH-I agonist
Luteolysis
OHSS
Ovary
alpha smooth muscle actin
angiopoietin 1
angiopoietin 2
angiopoietin receptor
cholesterol monooxygenase (side chain cleaving)
chorionic gonadotropin
cycline
estradiol
leuprorelin
progesterone
seric gonadotropin
steroidogenic acute regulatory protein
vasculotropin
vasculotropin receptor 2
angiogenesis
animal cell
animal experiment
animal model
animal tissue
apoptosis
article
blood vessel parameters
cell proliferation
controlled study
corpus luteum
down regulation
drug efficacy
drug mechanism
estradiol blood level
female
gonadotropin blood level
histopathology
in vivo study
luteal cell
nonhuman
ovary development
ovary hyperstimulation
peritoneal fluid level
priority journal
progesterone blood level
protein analysis
protein expression
protein localization
rat
steroidogenesis
vascular endothelium
vascular stability
Angiopoietin-1
Angiopoietin-2
Animals
Apoptosis
Blood Vessels
Cell Proliferation
Cholesterol Side-Chain Cleavage Enzyme
Corpus Luteum
Female
Fertility Agents, Female
Gonadal Steroid Hormones
Gonadotropins, Equine
Leuprolide
Ovarian Hyperstimulation Syndrome
Phosphoproteins
Rats
Rats, Sprague-Dawley
Receptor, TIE-2
Vascular Endothelial Growth Factor A
Vascular Endothelial Growth Factor Receptor-2
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03037207_v335_n2_p116_Scotti
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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