Effect of multiple doses of volatile anesthetics on heme enzymes

1. The effect of the administration of several doses of Enflurane and Isoflurane (2 ml/kg, i.p., daily) on heme metabolism and glucose levels was studied. 2. Liver and kidney δ-Aminolevulinic acid synthetase (ALA-S) activities were 85% (P < 0.01) induced after the third dose of Enflurane, instead...

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Detalles Bibliográficos
Autores principales: Buzaleh, A.M., Enriquez de Salamanca, R., Del Batlle, C.A.M.
Formato: JOUR
Materias:
acute porphyrias
anesthetics
Heme enzymes
porphyrinogenic drugs
5 aminolevulinate synthase
enflurane
glucose
inhalation anesthetic agent
isoflurane
liver enzyme
porphobilinogen deaminase
porphobilinogenase
unclassified drug
uroporphyrinogen
acute intermittent porphyria
animal experiment
animal tissue
article
controlled study
enzyme activity
enzyme blood level
enzyme induction
heme synthesis
intraperitoneal drug administration
mouse
nonhuman
priority journal
5-Aminolevulinate Synthetase
Ammonia-Lyases
Animal
Dose-Response Relationship, Drug
Enflurane
Glucose
Heme
Isoflurane
Kidney
Liver
Mice
Mice, Inbred Strains
Support, Non-U.S. Gov't
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03063623_v25_n6_p1179_Buzaleh
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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