Separation and quantification of hemoglobin A1c

Hemoglobin A(1c) is increased in patients with diabetes mellitus. An improved, specific, simple and highly sensitive method for the determination of HbA(1c) is described. Chromatographic separation of the different types of glycosylated hemoglobins from HbA''0 using cation-exchange resin i...

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Detalles Bibliográficos
Autores principales: Gonzalez, S., Tomio, J.M.
Formato: JOUR
Materias:
hemoglobin A1c
blood and hemopoietic system
chromatography
diabetes mellitus
endocrine system
human cell
laboratory
methodology
normal value
separation analysis
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03252957_v14_n3_p427_Gonzalez
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
Descripción
Sumario:Hemoglobin A(1c) is increased in patients with diabetes mellitus. An improved, specific, simple and highly sensitive method for the determination of HbA(1c) is described. Chromatographic separation of the different types of glycosylated hemoglobins from HbA''0 using cation-exchange resin in specific conditions of pH, temperature, load and columns is presented. Values of HbA(1c) in normal individuals in diabetic patients are given.

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