The birth of a platelet: A trip from bone marrow megakaryocytes to circulating platelets

Perhaps for being considered mere megakaryocyte cytoplasmic debris responsible for wound repair alone, platelets have had a secondary role when compared to other cellular blood components. However, in the last 20 years we have learned much more about these fascinating cells, which have slowly regain...

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Autores principales: Rivadeneyra, L., Ivani, P.C., Schattner, M., Pozner, R.G.
Formato: JOUR
Materias:
Chemokines
Cytokines
Hematopoiesis
Hemostasis
Megakaryocytes
Megakaryopoiesis
Platelet biogenesis
Platelets
Thrombopoiesis
Thrombosis
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03252957_v50_n2_p233_Rivadeneyra
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id todo:paper_03252957_v50_n2_p233_Rivadeneyra
record_format dspace
spelling todo:paper_03252957_v50_n2_p233_Rivadeneyra2023-10-03T15:23:44Z The birth of a platelet: A trip from bone marrow megakaryocytes to circulating platelets Rivadeneyra, L. Ivani, P.C. Schattner, M. Pozner, R.G. Chemokines Cytokines Hematopoiesis Hemostasis Megakaryocytes Megakaryopoiesis Platelet biogenesis Platelets Thrombopoiesis Thrombosis Perhaps for being considered mere megakaryocyte cytoplasmic debris responsible for wound repair alone, platelets have had a secondary role when compared to other cellular blood components. However, in the last 20 years we have learned much more about these fascinating cells, which have slowly regained a prominent place in hematology. This review discusses the most outstanding and novel contributions on platelet biogenesis, its regulation by the bone marrow microenvironment and humoral factors, analyzing from megakaryocyte generation to platelet release. Fil:Pozner, R.G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_03252957_v50_n2_p233_Rivadeneyra
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Chemokines
Cytokines
Hematopoiesis
Hemostasis
Megakaryocytes
Megakaryopoiesis
Platelet biogenesis
Platelets
Thrombopoiesis
Thrombosis
spellingShingle Chemokines
Cytokines
Hematopoiesis
Hemostasis
Megakaryocytes
Megakaryopoiesis
Platelet biogenesis
Platelets
Thrombopoiesis
Thrombosis
Rivadeneyra, L.
Ivani, P.C.
Schattner, M.
Pozner, R.G.
The birth of a platelet: A trip from bone marrow megakaryocytes to circulating platelets
topic_facet Chemokines
Cytokines
Hematopoiesis
Hemostasis
Megakaryocytes
Megakaryopoiesis
Platelet biogenesis
Platelets
Thrombopoiesis
Thrombosis
description Perhaps for being considered mere megakaryocyte cytoplasmic debris responsible for wound repair alone, platelets have had a secondary role when compared to other cellular blood components. However, in the last 20 years we have learned much more about these fascinating cells, which have slowly regained a prominent place in hematology. This review discusses the most outstanding and novel contributions on platelet biogenesis, its regulation by the bone marrow microenvironment and humoral factors, analyzing from megakaryocyte generation to platelet release.
format JOUR
author Rivadeneyra, L.
Ivani, P.C.
Schattner, M.
Pozner, R.G.
author_facet Rivadeneyra, L.
Ivani, P.C.
Schattner, M.
Pozner, R.G.
author_sort Rivadeneyra, L.
title The birth of a platelet: A trip from bone marrow megakaryocytes to circulating platelets
title_short The birth of a platelet: A trip from bone marrow megakaryocytes to circulating platelets
title_full The birth of a platelet: A trip from bone marrow megakaryocytes to circulating platelets
title_fullStr The birth of a platelet: A trip from bone marrow megakaryocytes to circulating platelets
title_full_unstemmed The birth of a platelet: A trip from bone marrow megakaryocytes to circulating platelets
title_sort birth of a platelet: a trip from bone marrow megakaryocytes to circulating platelets
url http://hdl.handle.net/20.500.12110/paper_03252957_v50_n2_p233_Rivadeneyra
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