Interaction of Rab31 and OCRL-1 in oligodendrocytes: Its role in transport of mannose 6-phosphate receptors

Rab31, a protein that we cloned from an oligodendrocyte cDNA library, is required for transport of mannose 6-phosphate receptors (MPRs) from the trans-Golgi network (TGN) to endosomes and for Golgi/TGN organization. Here we extend the knowledge of the mechanism of action of Rab31 by demonstrating it...

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Detalles Bibliográficos
Autores principales: Rodriguez-Gabin, A.G., Ortiz, E., Demoliner, K., Si, Q., Almazan, G., Larocca, J.N.
Formato: JOUR
Materias:
Endosomes
Myelin
Oligodendrocytes
Phosphatidylinositol 4,5-diphosphate 5-phosphatase
Rab proteins
Signaling
Trans-Golgi network
Vesicle transport
cation
CD36 antigen
phosphatase
phosphatidylinositol 4,5 diphosphate 5 phosphatase
Rab protein
small interfering RNA
somatomedin B receptor
unclassified drug
animal cell
animal tissue
article
cell lysate
controlled study
demyelination
endosome
experiment
female
Golgi complex
heterozygote detection
human
human cell
immunoprecipitation
mutation
nerve cell culture
nonhuman
oligodendroglia
priority journal
protein interaction
protein protein interaction
rat
stomatitis
trans Golgi network
two hybrid system
Vesicular stomatitis virus
yeast
Animals
Antigens, CD
Brain
Cations
Cell Membrane
Cells, Cultured
Hela Cells
Humans
Mice
Oligodendroglia
Phosphoric Monoester Hydrolases
Platelet Membrane Glycoproteins
Protein Binding
Protein Conformation
rab GTP-Binding Proteins
Rats
Receptor, IGF Type 2
trans-Golgi Network
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03604012_v88_n3_p589_RodriguezGabin
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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