Synthesis of |24‐14C|‐3β,14β,20ε‐trihydroxy‐23‐nor‐5β‐cholanoic acid

The synthesis of |24‐14C|‐3β,14β,20ε‐trihydroxy‐23‐nor‐5β‐cholanoic acid was accomplished by Reformatsky reaction of ethyl |1‐14C|‐bromo acetate with 3β‐acetoxy‐14β‐hydroxy‐5β‐pregnan‐20‐one which was obtained from digitoxigenin. The final and intermediate products were characterized by spectroscopi...

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Autores principales: Maier, M.S., Seldes, A.M., Gros, E.G.
Formato: JOUR
Materias:
Reformatsky reaction
Synthesis
|24‐14C|‐3β,14β,20ε‐Trihydroxy‐23‐nor‐5β‐cholanoic acid
radioisotope
3beta,14beta,20 trihydroxy 23 norcholanic acid c 14
methodology
nonhuman
priority journal
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03624803_v22_n8_p833_Maier
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
id todo:paper_03624803_v22_n8_p833_Maier
record_format dspace
spelling todo:paper_03624803_v22_n8_p833_Maier2023-10-03T15:27:05Z Synthesis of |24‐14C|‐3β,14β,20ε‐trihydroxy‐23‐nor‐5β‐cholanoic acid Maier, M.S. Seldes, A.M. Gros, E.G. Reformatsky reaction Synthesis |24‐14C|‐3β,14β,20ε‐Trihydroxy‐23‐nor‐5β‐cholanoic acid radioisotope 3beta,14beta,20 trihydroxy 23 norcholanic acid c 14 methodology nonhuman priority journal The synthesis of |24‐14C|‐3β,14β,20ε‐trihydroxy‐23‐nor‐5β‐cholanoic acid was accomplished by Reformatsky reaction of ethyl |1‐14C|‐bromo acetate with 3β‐acetoxy‐14β‐hydroxy‐5β‐pregnan‐20‐one which was obtained from digitoxigenin. The final and intermediate products were characterized by spectroscopic (IR, 1H and 13C‐NMR, MS) methods. Copyright © 1985 John Wiley & Sons, Ltd. Fil:Maier, M.S. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Seldes, A.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Gros, E.G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_03624803_v22_n8_p833_Maier
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Reformatsky reaction
Synthesis
|24‐14C|‐3β,14β,20ε‐Trihydroxy‐23‐nor‐5β‐cholanoic acid
radioisotope
3beta,14beta,20 trihydroxy 23 norcholanic acid c 14
methodology
nonhuman
priority journal
spellingShingle Reformatsky reaction
Synthesis
|24‐14C|‐3β,14β,20ε‐Trihydroxy‐23‐nor‐5β‐cholanoic acid
radioisotope
3beta,14beta,20 trihydroxy 23 norcholanic acid c 14
methodology
nonhuman
priority journal
Maier, M.S.
Seldes, A.M.
Gros, E.G.
Synthesis of |24‐14C|‐3β,14β,20ε‐trihydroxy‐23‐nor‐5β‐cholanoic acid
topic_facet Reformatsky reaction
Synthesis
|24‐14C|‐3β,14β,20ε‐Trihydroxy‐23‐nor‐5β‐cholanoic acid
radioisotope
3beta,14beta,20 trihydroxy 23 norcholanic acid c 14
methodology
nonhuman
priority journal
description The synthesis of |24‐14C|‐3β,14β,20ε‐trihydroxy‐23‐nor‐5β‐cholanoic acid was accomplished by Reformatsky reaction of ethyl |1‐14C|‐bromo acetate with 3β‐acetoxy‐14β‐hydroxy‐5β‐pregnan‐20‐one which was obtained from digitoxigenin. The final and intermediate products were characterized by spectroscopic (IR, 1H and 13C‐NMR, MS) methods. Copyright © 1985 John Wiley & Sons, Ltd.
format JOUR
author Maier, M.S.
Seldes, A.M.
Gros, E.G.
author_facet Maier, M.S.
Seldes, A.M.
Gros, E.G.
author_sort Maier, M.S.
title Synthesis of |24‐14C|‐3β,14β,20ε‐trihydroxy‐23‐nor‐5β‐cholanoic acid
title_short Synthesis of |24‐14C|‐3β,14β,20ε‐trihydroxy‐23‐nor‐5β‐cholanoic acid
title_full Synthesis of |24‐14C|‐3β,14β,20ε‐trihydroxy‐23‐nor‐5β‐cholanoic acid
title_fullStr Synthesis of |24‐14C|‐3β,14β,20ε‐trihydroxy‐23‐nor‐5β‐cholanoic acid
title_full_unstemmed Synthesis of |24‐14C|‐3β,14β,20ε‐trihydroxy‐23‐nor‐5β‐cholanoic acid
title_sort synthesis of |24‐14c|‐3β,14β,20ε‐trihydroxy‐23‐nor‐5β‐cholanoic acid
url http://hdl.handle.net/20.500.12110/paper_03624803_v22_n8_p833_Maier
work_keys_str_mv AT maierms synthesisof2414c3b14b20etrihydroxy23nor5bcholanoicacid
AT seldesam synthesisof2414c3b14b20etrihydroxy23nor5bcholanoicacid
AT groseg synthesisof2414c3b14b20etrihydroxy23nor5bcholanoicacid
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