Comparison of subcutaneous apomorphine versus dispersible madopar latency and effect duration in parkinson's disease patients: A double-blind single-dose study

Twelve parkinsonian patients with severely fluctuating symptoms were given a single dose of apomorphine or Dispersible Madopar on 2 consecutive days, to confirm the latter drug's usefulness in 'off' period rescue. According to our results, apomorphine proved faster in reverting '...

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Autores principales: Merello, M., Pikielny, R., Cammarota, A., Leiguarda, R.
Formato: JOUR
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Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03625664_v20_n2_p165_Merello
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spelling todo:paper_03625664_v20_n2_p165_Merello2023-10-03T15:27:25Z Comparison of subcutaneous apomorphine versus dispersible madopar latency and effect duration in parkinson's disease patients: A double-blind single-dose study Merello, M. Pikielny, R. Cammarota, A. Leiguarda, R. 'On-off' periods Apomorphine Dispersible Madopar Motor fluctuation Parkinson's disease apomorphine benserazide plus levodopa britaject levodopa unclassified drug adult article clinical article clinical trial controlled clinical trial controlled study double blind procedure female human male motor dysfunction on off phenomenon Parkinson disease priority journal subcutaneous drug administration Twelve parkinsonian patients with severely fluctuating symptoms were given a single dose of apomorphine or Dispersible Madopar on 2 consecutive days, to confirm the latter drug's usefulness in 'off' period rescue. According to our results, apomorphine proved faster in reverting 'off' periods and should still be regarded as the drug of choice for this treatment modality. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_03625664_v20_n2_p165_Merello
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic 'On-off' periods
Apomorphine
Dispersible Madopar
Motor fluctuation
Parkinson's disease
apomorphine
benserazide plus levodopa
britaject
levodopa
unclassified drug
adult
article
clinical article
clinical trial
controlled clinical trial
controlled study
double blind procedure
female
human
male
motor dysfunction
on off phenomenon
Parkinson disease
priority journal
subcutaneous drug administration
spellingShingle 'On-off' periods
Apomorphine
Dispersible Madopar
Motor fluctuation
Parkinson's disease
apomorphine
benserazide plus levodopa
britaject
levodopa
unclassified drug
adult
article
clinical article
clinical trial
controlled clinical trial
controlled study
double blind procedure
female
human
male
motor dysfunction
on off phenomenon
Parkinson disease
priority journal
subcutaneous drug administration
Merello, M.
Pikielny, R.
Cammarota, A.
Leiguarda, R.
Comparison of subcutaneous apomorphine versus dispersible madopar latency and effect duration in parkinson's disease patients: A double-blind single-dose study
topic_facet 'On-off' periods
Apomorphine
Dispersible Madopar
Motor fluctuation
Parkinson's disease
apomorphine
benserazide plus levodopa
britaject
levodopa
unclassified drug
adult
article
clinical article
clinical trial
controlled clinical trial
controlled study
double blind procedure
female
human
male
motor dysfunction
on off phenomenon
Parkinson disease
priority journal
subcutaneous drug administration
description Twelve parkinsonian patients with severely fluctuating symptoms were given a single dose of apomorphine or Dispersible Madopar on 2 consecutive days, to confirm the latter drug's usefulness in 'off' period rescue. According to our results, apomorphine proved faster in reverting 'off' periods and should still be regarded as the drug of choice for this treatment modality.
format JOUR
author Merello, M.
Pikielny, R.
Cammarota, A.
Leiguarda, R.
author_facet Merello, M.
Pikielny, R.
Cammarota, A.
Leiguarda, R.
author_sort Merello, M.
title Comparison of subcutaneous apomorphine versus dispersible madopar latency and effect duration in parkinson's disease patients: A double-blind single-dose study
title_short Comparison of subcutaneous apomorphine versus dispersible madopar latency and effect duration in parkinson's disease patients: A double-blind single-dose study
title_full Comparison of subcutaneous apomorphine versus dispersible madopar latency and effect duration in parkinson's disease patients: A double-blind single-dose study
title_fullStr Comparison of subcutaneous apomorphine versus dispersible madopar latency and effect duration in parkinson's disease patients: A double-blind single-dose study
title_full_unstemmed Comparison of subcutaneous apomorphine versus dispersible madopar latency and effect duration in parkinson's disease patients: A double-blind single-dose study
title_sort comparison of subcutaneous apomorphine versus dispersible madopar latency and effect duration in parkinson's disease patients: a double-blind single-dose study
url http://hdl.handle.net/20.500.12110/paper_03625664_v20_n2_p165_Merello
work_keys_str_mv AT merellom comparisonofsubcutaneousapomorphineversusdispersiblemadoparlatencyandeffectdurationinparkinsonsdiseasepatientsadoubleblindsingledosestudy
AT pikielnyr comparisonofsubcutaneousapomorphineversusdispersiblemadoparlatencyandeffectdurationinparkinsonsdiseasepatientsadoubleblindsingledosestudy
AT cammarotaa comparisonofsubcutaneousapomorphineversusdispersiblemadoparlatencyandeffectdurationinparkinsonsdiseasepatientsadoubleblindsingledosestudy
AT leiguardar comparisonofsubcutaneousapomorphineversusdispersiblemadoparlatencyandeffectdurationinparkinsonsdiseasepatientsadoubleblindsingledosestudy
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