Morphine inhibits an α9-acetylcholine nicotinic receptor-mediated response by a mechanism which does not involve opioid receptors

Nicotinic acetylcholine (nACh) receptors are known to be targets for modulation by a number of substances, including the opiates. It is known that acetylcholine (ACh) coexists with opioid peptides in cochlear efferent neurons, and such a colocalization has been proposed for the vestibular system. In...

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Detalles Bibliográficos
Autores principales: Lioudyno, M.I., Verbitsky, M., Holt, J.C., Elgoyhen, A.B., Guth, P.S.
Formato: JOUR
Materias:
Efferent
Hair cell
Interaction
Morphine
nACh receptor
Vestibular system
morphine
nicotinic receptor
opiate receptor
acetylcholine
Chrna9 protein, mouse
naloxone
narcotic agent
narcotic antagonist
animal cell
animal experiment
article
controlled study
efferent nerve
frog
hair cell
nonhuman
patch clamp
priority journal
receptor blocking
vestibular nervous system
Xenopus laevis
animal
drug effect
electric conductivity
metabolism
oocyte
physiology
Acetylcholine
Animals
Electric Conductivity
Hair Cells
Naloxone
Narcotic Antagonists
Narcotics
Oocytes
Rana pipiens
Receptors, Nicotinic
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03785955_v149_n1-2_p167_Lioudyno
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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