Sjögren's in adult still's disease?
The objective of the study was to search for clinical, ophthalmological and seroiogical manifestations of Sjögren's syndrome in patients with adult onset Still's Disease (AOSD). Eight consecutive patients with AOSD were evaluated. In all cases a standardized questionnaire to disclose sicca...
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todo:paper_07703198_v15_n2_p133_SanchezLoria2023-10-03T15:39:46Z Sjögren's in adult still's disease? Sanchez Loria, D.M. Moreno Alvarez, M.J. Barceló, H.A. Catoggio, L.J. Maldonado Cocco, J.A. Adult Onset Still's Disease Keratoconjunctivitis Sicca Sialoadenitis Sjögren's Syndrome antinuclear antibody rheumatoid factor auranofin chloroquine indometacin methylprednisolone naproxen piroxicam prednisone adult adult onset Still disease article biopsy female fluorescent antibody technique human keratoconjunctivitis sicca male metabolism middle aged minor saliva gland pathology questionnaire serology sialoadenitis Sjoegren syndrome adult disease clinical article controlled study juvenile rheumatoid arthritis keratoconjunctivitis oral drug administration priority journal sialoadenitis sjoegren syndrome Adult Antibodies, Antinuclear Biopsy Female Fluorescent Antibody Technique, Indirect Humans Keratoconjunctivitis Sicca Male Middle Aged Questionnaires Rheumatoid Factor Salivary Glands, Minor Serologic Tests Sialadenitis Sjogren's Syndrome Still's Disease, Adult-Onset The objective of the study was to search for clinical, ophthalmological and seroiogical manifestations of Sjögren's syndrome in patients with adult onset Still's Disease (AOSD). Eight consecutive patients with AOSD were evaluated. In all cases a standardized questionnaire to disclose sicca symptoms as well as extraglandular manifestations commonly associated with Sjögren's syndrome (SS) was conducted. Ophthalmological and serological evaluation was undertaken in all patients. Oral involvement was investigated by minor salivary gland biopsy in 7 patients. One case presented symptomatic keratoconjunctivitis sicca and grade III Chisholm labial biopsy. A further 2 patients had grade IV (4 foci per 4 mm2) salivary gland biopsy, in the absence of xerostomia or xerophthalmia. The search for autoantibodies proved negative throughout. It was concluded that focal sialoadenitis was not uncommon in our patients with AOSD. Whether this finding corresponds to a true SS is not yet clearly determined. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_07703198_v15_n2_p133_SanchezLoria |
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Universidad de Buenos Aires |
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I-28 |
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R-134 |
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Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
Adult Onset Still's Disease Keratoconjunctivitis Sicca Sialoadenitis Sjögren's Syndrome antinuclear antibody rheumatoid factor auranofin chloroquine indometacin methylprednisolone naproxen piroxicam prednisone adult adult onset Still disease article biopsy female fluorescent antibody technique human keratoconjunctivitis sicca male metabolism middle aged minor saliva gland pathology questionnaire serology sialoadenitis Sjoegren syndrome adult disease clinical article controlled study juvenile rheumatoid arthritis keratoconjunctivitis oral drug administration priority journal sialoadenitis sjoegren syndrome Adult Antibodies, Antinuclear Biopsy Female Fluorescent Antibody Technique, Indirect Humans Keratoconjunctivitis Sicca Male Middle Aged Questionnaires Rheumatoid Factor Salivary Glands, Minor Serologic Tests Sialadenitis Sjogren's Syndrome Still's Disease, Adult-Onset |
| spellingShingle |
Adult Onset Still's Disease Keratoconjunctivitis Sicca Sialoadenitis Sjögren's Syndrome antinuclear antibody rheumatoid factor auranofin chloroquine indometacin methylprednisolone naproxen piroxicam prednisone adult adult onset Still disease article biopsy female fluorescent antibody technique human keratoconjunctivitis sicca male metabolism middle aged minor saliva gland pathology questionnaire serology sialoadenitis Sjoegren syndrome adult disease clinical article controlled study juvenile rheumatoid arthritis keratoconjunctivitis oral drug administration priority journal sialoadenitis sjoegren syndrome Adult Antibodies, Antinuclear Biopsy Female Fluorescent Antibody Technique, Indirect Humans Keratoconjunctivitis Sicca Male Middle Aged Questionnaires Rheumatoid Factor Salivary Glands, Minor Serologic Tests Sialadenitis Sjogren's Syndrome Still's Disease, Adult-Onset Sanchez Loria, D.M. Moreno Alvarez, M.J. Barceló, H.A. Catoggio, L.J. Maldonado Cocco, J.A. Sjögren's in adult still's disease? |
| topic_facet |
Adult Onset Still's Disease Keratoconjunctivitis Sicca Sialoadenitis Sjögren's Syndrome antinuclear antibody rheumatoid factor auranofin chloroquine indometacin methylprednisolone naproxen piroxicam prednisone adult adult onset Still disease article biopsy female fluorescent antibody technique human keratoconjunctivitis sicca male metabolism middle aged minor saliva gland pathology questionnaire serology sialoadenitis Sjoegren syndrome adult disease clinical article controlled study juvenile rheumatoid arthritis keratoconjunctivitis oral drug administration priority journal sialoadenitis sjoegren syndrome Adult Antibodies, Antinuclear Biopsy Female Fluorescent Antibody Technique, Indirect Humans Keratoconjunctivitis Sicca Male Middle Aged Questionnaires Rheumatoid Factor Salivary Glands, Minor Serologic Tests Sialadenitis Sjogren's Syndrome Still's Disease, Adult-Onset |
| description |
The objective of the study was to search for clinical, ophthalmological and seroiogical manifestations of Sjögren's syndrome in patients with adult onset Still's Disease (AOSD). Eight consecutive patients with AOSD were evaluated. In all cases a standardized questionnaire to disclose sicca symptoms as well as extraglandular manifestations commonly associated with Sjögren's syndrome (SS) was conducted. Ophthalmological and serological evaluation was undertaken in all patients. Oral involvement was investigated by minor salivary gland biopsy in 7 patients. One case presented symptomatic keratoconjunctivitis sicca and grade III Chisholm labial biopsy. A further 2 patients had grade IV (4 foci per 4 mm2) salivary gland biopsy, in the absence of xerostomia or xerophthalmia. The search for autoantibodies proved negative throughout. It was concluded that focal sialoadenitis was not uncommon in our patients with AOSD. Whether this finding corresponds to a true SS is not yet clearly determined. |
| format |
JOUR |
| author |
Sanchez Loria, D.M. Moreno Alvarez, M.J. Barceló, H.A. Catoggio, L.J. Maldonado Cocco, J.A. |
| author_facet |
Sanchez Loria, D.M. Moreno Alvarez, M.J. Barceló, H.A. Catoggio, L.J. Maldonado Cocco, J.A. |
| author_sort |
Sanchez Loria, D.M. |
| title |
Sjögren's in adult still's disease? |
| title_short |
Sjögren's in adult still's disease? |
| title_full |
Sjögren's in adult still's disease? |
| title_fullStr |
Sjögren's in adult still's disease? |
| title_full_unstemmed |
Sjögren's in adult still's disease? |
| title_sort |
sjögren's in adult still's disease? |
| url |
http://hdl.handle.net/20.500.12110/paper_07703198_v15_n2_p133_SanchezLoria |
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1807314781092184064 |