Steroid protection in the experimental autoimmune encephalomyelitis model of multiple sclerosis

Objectives: Based on evidence that pregnant women with multiple sclerosis (MS) show a decline in the relapse rate during the third trimester and an increase during the first 3 months postpartum, the suggestion was made that high levels of circulating sex steroids are responsible for pregnancy-mediat...

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Detalles Bibliográficos
Autores principales:	Garay, L., Gonzalez Deniselle, M.C., Gierman, L., Meyer, M., Lima, A., Roig, P., De Nicola, A.F.
Formato:	JOUR
Materias:	Estradiol Experimental autoimmune encephalomyelitis Multiple sclerosis Myelination Neuroprotection Progesterone 1,3,5 tris(4 hydroxyphenyl) 4 propylpyrazole adenosine triphosphatase (potassium sodium) brain derived neurotrophic factor estradiol estriol ethinylestradiol fluasterone glucocorticoid medroxyprogesterone myelin basic protein myelin oligodendrocyte glycoprotein prasterone progesterone proteolipid protein tetrahydroprogesterone allergic encephalomyelitis brain function cell infiltration cell proliferation cellular immunity demyelination disease course drug activity drug effect drug megadose estrogen activity hormonal regulation hormone action human low drug dose multiple sclerosis myelin sheath myelination neuroprotection nonhuman pathogenesis priority journal protein expression quantitative analysis review theoretical model third trimester pregnancy Animals Brain-Derived Neurotrophic Factor Central Nervous System Disease Models, Animal Drug Synergism Drug Therapy, Combination Encephalomyelitis, Autoimmune, Experimental Female Humans Mice Mice, Inbred C57BL Multiple Sclerosis Myelin Basic Proteins Myelin Proteolipid Protein Nerve Fibers, Myelinated Neurosecretory Systems RNA, Messenger Sodium-Potassium-Exchanging ATPase Treatment Outcome Up-Regulation
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_10217401_v15_n1_p76_Garay
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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