Testosterone induction of prostaglandin-endoperoxide synthase 2 expression and prostaglandin F 2α production in hamster Leydig cells

We have previously observed expression of prostaglandin-endoperoxide synthase 2 (PTGS2), the key enzyme in the biosynthesis of prostaglandins (PGs), in reproductively active Syrian hamster Leydig cells, and reported an inhibitory role of PGF 2α on hamster testicular steroidogenesis. In this study, w...

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Detalles Bibliográficos
Autores principales:	Matzkin, M.E., Gonzalez-Calvar, S.I., Mayerhofer, A., Calandra, R.S., Frungieri, M.B.
Formato:	JOUR
Materias:	1,4 diamino 1,4 bis(2 aminophenylthio) 2,3 dicyanobutadiene androgen receptor antiandrogen bicalutamide luteinizing hormone mitogen activated protein kinase 1 mitogen activated protein kinase 3 prostaglandin endoperoxide synthase 2 prostaglandin F2 alpha prostaglandin synthase testosterone unclassified drug animal cell animal experiment animal tissue article controlled study enzyme activation hormonal regulation Leydig cell male nonhuman photoperiodicity priority journal prostaglandin synthesis protein expression protein induction protein phosphorylation protein synthesis sexual development spermatogenesis steroidogenesis Syrian hamster Androgen Antagonists Animals Cells, Cultured Chorionic Gonadotropin Cricetinae Cyclooxygenase 2 Dinoprost Enzyme Induction Leydig Cells Luteinizing Hormone Male Mesocricetus Mitogen-Activated Protein Kinases Phosphorylation Photoperiod Protein Kinase Inhibitors Receptors, Androgen Sexual Development Signal Transduction Testosterone Up-Regulation Mesocricetus auratus
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_14701626_v138_n1_p163_Matzkin
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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