A Multilayer Network Approach for Guiding Drug Repositioning in Neglected Diseases

Drug development for neglected diseases has been historically hampered due to lack of market incentives. The advent of public domain resources containing chemical information from high throughput screenings is changing the landscape of drug discovery for these diseases. In this work we took advantag...

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Detalles Bibliográficos
Autores principales: Berenstein, A.J., Magariños, M.P., Chernomoretz, A., Agüero, F.
Formato: JOUR
Materias:
chemical compound
peptide deformylase
antiparasitic agent
Article
biological activity
drug repositioning
genome
high throughput screening
Kinetoplastida
mathematical computing
neglected disease
nonhuman
Plasmodium falciparum
protein analysis
protein domain
sequence analysis
Trypanosoma cruzi
animal
biology
drug development
human
isolation and purification
mouse
Neglected Diseases
procedures
Animals
Antiparasitic Agents
Computational Biology
Drug Discovery
Drug Repositioning
Humans
Mice
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_19352727_v10_n1_p_Berenstein
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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