Coronary microvascular dysfunction in women with nonobstructive ischemic heart disease as assessed by positron emission tomography

Traditional approaches for risk assessment of ischemic heart disease (IHD) are based on the physiological consequences of an epicardial coronary stenosis. Of note, normal coronary arteries or nonobstructive coronary artery disease (CAD) is a common finding in women with signs and symptoms of ischemi...

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Autores principales: Campisi, R., Marengo, F.D.
Formato: JOUR
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Acceso en línea:http://hdl.handle.net/20.500.12110/paper_22233652_v7_n2_p196_Campisi
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spelling todo:paper_22233652_v7_n2_p196_Campisi2023-10-03T16:40:43Z Coronary microvascular dysfunction in women with nonobstructive ischemic heart disease as assessed by positron emission tomography Campisi, R. Marengo, F.D. Coronary flow reserve (CFR) Ischemic heart disease (IHD) Positron emission tomography (PET) Women atherosclerosis clinical assessment coronary artery disease diagnostic accuracy endothelial dysfunction heart muscle blood flow human intermethod comparison ischemic heart disease microangiopathy myocardial perfusion imaging positron emission tomography prognosis Review risk assessment single photon emission computed tomography women's health Traditional approaches for risk assessment of ischemic heart disease (IHD) are based on the physiological consequences of an epicardial coronary stenosis. Of note, normal coronary arteries or nonobstructive coronary artery disease (CAD) is a common finding in women with signs and symptoms of ischemia. Therefore, assessment of risk based on a coronary stenosis approach may fail in women. Positron emission tomography (PET) quantifies absolute myocardial blood flow (MBF) which may help to elucidate other mechanisms involved such as endothelial dysfunction and alterations in the smooth muscle cell relaxation responsible for IHD in women. The objective of the present review is to describe the current state of the art of PET imaging in assessing IHD in women with nonobstructive CAD. © Cardiovascular Diagnosis and Therapy. All rights reserved. Fil:Marengo, F.D. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_22233652_v7_n2_p196_Campisi
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic Coronary flow reserve (CFR)
Ischemic heart disease (IHD)
Positron emission tomography (PET)
Women
atherosclerosis
clinical assessment
coronary artery disease
diagnostic accuracy
endothelial dysfunction
heart muscle blood flow
human
intermethod comparison
ischemic heart disease
microangiopathy
myocardial perfusion imaging
positron emission tomography
prognosis
Review
risk assessment
single photon emission computed tomography
women's health
spellingShingle Coronary flow reserve (CFR)
Ischemic heart disease (IHD)
Positron emission tomography (PET)
Women
atherosclerosis
clinical assessment
coronary artery disease
diagnostic accuracy
endothelial dysfunction
heart muscle blood flow
human
intermethod comparison
ischemic heart disease
microangiopathy
myocardial perfusion imaging
positron emission tomography
prognosis
Review
risk assessment
single photon emission computed tomography
women's health
Campisi, R.
Marengo, F.D.
Coronary microvascular dysfunction in women with nonobstructive ischemic heart disease as assessed by positron emission tomography
topic_facet Coronary flow reserve (CFR)
Ischemic heart disease (IHD)
Positron emission tomography (PET)
Women
atherosclerosis
clinical assessment
coronary artery disease
diagnostic accuracy
endothelial dysfunction
heart muscle blood flow
human
intermethod comparison
ischemic heart disease
microangiopathy
myocardial perfusion imaging
positron emission tomography
prognosis
Review
risk assessment
single photon emission computed tomography
women's health
description Traditional approaches for risk assessment of ischemic heart disease (IHD) are based on the physiological consequences of an epicardial coronary stenosis. Of note, normal coronary arteries or nonobstructive coronary artery disease (CAD) is a common finding in women with signs and symptoms of ischemia. Therefore, assessment of risk based on a coronary stenosis approach may fail in women. Positron emission tomography (PET) quantifies absolute myocardial blood flow (MBF) which may help to elucidate other mechanisms involved such as endothelial dysfunction and alterations in the smooth muscle cell relaxation responsible for IHD in women. The objective of the present review is to describe the current state of the art of PET imaging in assessing IHD in women with nonobstructive CAD. © Cardiovascular Diagnosis and Therapy. All rights reserved.
format JOUR
author Campisi, R.
Marengo, F.D.
author_facet Campisi, R.
Marengo, F.D.
author_sort Campisi, R.
title Coronary microvascular dysfunction in women with nonobstructive ischemic heart disease as assessed by positron emission tomography
title_short Coronary microvascular dysfunction in women with nonobstructive ischemic heart disease as assessed by positron emission tomography
title_full Coronary microvascular dysfunction in women with nonobstructive ischemic heart disease as assessed by positron emission tomography
title_fullStr Coronary microvascular dysfunction in women with nonobstructive ischemic heart disease as assessed by positron emission tomography
title_full_unstemmed Coronary microvascular dysfunction in women with nonobstructive ischemic heart disease as assessed by positron emission tomography
title_sort coronary microvascular dysfunction in women with nonobstructive ischemic heart disease as assessed by positron emission tomography
url http://hdl.handle.net/20.500.12110/paper_22233652_v7_n2_p196_Campisi
work_keys_str_mv AT campisir coronarymicrovasculardysfunctioninwomenwithnonobstructiveischemicheartdiseaseasassessedbypositronemissiontomography
AT marengofd coronarymicrovasculardysfunctioninwomenwithnonobstructiveischemicheartdiseaseasassessedbypositronemissiontomography
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