Naturally occurring compounds elicit hiv-1 replication in chronically infected promonocytic cells

Since antiretroviral therapy suppresses but does not eradicate HIV-1 infection, methods to purge viral reservoirs are required. Many strategies involve the reactivation of chronically HIV infected cells to induce the expression of integrated viral genome. In this study, five bioactive compounds, the...

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Detalles Bibliográficos
Autores principales:	Barquero, A.A., Dávola, M.E., Riva, D.A., Mersich, S.E., Alché, L.E.
Formato:	JOUR
Materias:	1 cinnamoyl 3,11 dihydroxymeliacarpin 22,23 dihydroxystigmast 4 en 3 one 3beta bromo 5alpha,22,23 trihydroxystigmastan 6 one antigen p24 antiretrovirus agent curcumin interleukin 2 interleukin 6 interleukin 7 nordihydroguaiaretic acid plant medicinal product reactive oxygen metabolite stigmasterol tumor necrosis factor alpha unclassified drug 1-cinnamoyl-3,11-dihydroxymeliacarpin 22,23-dihydroxystigmast-4-en-3-one 3-bromo-5,22,23-trihydroxystigmastan-6-one biological factor cholestane derivative limonoid plant extract article cell viability controlled study cytokine production cytokine release drug mechanism human human cell Human immunodeficiency virus 1 infection lymphocyte monocyte macrophage precursor cell oxidation reduction state protein expression virus reactivation virus replication analogs and derivatives cell line DNA replication drug effects Human immunodeficiency virus 1 Human immunodeficiency virus infection metabolism monocyte tumor cell line U937 cell line virology Biological Factors Cell Line Cell Line, Tumor Cholestanones Curcumin DNA Replication HIV Infections HIV-1 Humans Interleukin-6 Limonins Masoprocol Monocytes Plant Extracts Reactive Oxygen Species Stigmasterol Tumor Necrosis Factor-alpha U937 Cells Virus Replication
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_23146133_v2014_n_p_Barquero
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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